Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

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10 Scopus citations

Abstract

Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

Original languageEnglish (US)
Pages (from-to)955-957
Number of pages3
JournalNeuron
Volume71
Issue number6
DOIs
StatePublished - Sep 22 2011

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ASJC Scopus subject areas

  • Neuroscience(all)

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