Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

Research output: Contribution to journalShort survey

9 Citations (Scopus)

Abstract

Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

Original languageEnglish (US)
Pages (from-to)955-957
Number of pages3
JournalNeuron
Volume71
Issue number6
DOIs
StatePublished - Sep 22 2011

Fingerprint

Frontotemporal Dementia
Wnt Signaling Pathway
Pathology
Neurons
Mutation
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia. / Korade, Zeljka; Mirnics, Karoly.

In: Neuron, Vol. 71, No. 6, 22.09.2011, p. 955-957.

Research output: Contribution to journalShort survey

@article{01791369e6b54d94875f6a5472d45412,
title = "Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia",
abstract = "Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.",
author = "Zeljka Korade and Karoly Mirnics",
year = "2011",
month = "9",
day = "22",
doi = "10.1016/j.neuron.2011.09.002",
language = "English (US)",
volume = "71",
pages = "955--957",
journal = "Neuron",
issn = "0896-6273",
publisher = "Cell Press",
number = "6",

}

TY - JOUR

T1 - Wnt Signaling as a Potential Therapeutic Target for Frontotemporal Dementia

AU - Korade, Zeljka

AU - Mirnics, Karoly

PY - 2011/9/22

Y1 - 2011/9/22

N2 - Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

AB - Progranulin mutations result in frontotemporal dementia, but the underlying pathophysiology has remained largely unexplained. New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology.

UR - http://www.scopus.com/inward/record.url?scp=80053129862&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053129862&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2011.09.002

DO - 10.1016/j.neuron.2011.09.002

M3 - Short survey

VL - 71

SP - 955

EP - 957

JO - Neuron

JF - Neuron

SN - 0896-6273

IS - 6

ER -