### Abstract

In this paper we construct a mathematical model for DNA replication based on Shannon's mathematical theory for communication. We treat DNA replication as a communication channel. We show that the mean replication rate is maximal with four nucleotide bases under the primary assumption that the pairing time of the G-C bases is between 1.65 and 3 times the pairing time of the A-T bases.

Original language | English (US) |
---|---|

Pages (from-to) | 727-733 |

Number of pages | 7 |

Journal | Bulletin of Mathematical Biology |

Volume | 68 |

Issue number | 3 |

DOIs | |

Publication status | Published - Apr 1 2006 |

### Fingerprint

### Keywords

- Base pairing time
- Communication channel
- DNA replication
- Data rate

### ASJC Scopus subject areas

- Neuroscience(all)
- Immunology
- Mathematics(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Environmental Science(all)
- Pharmacology
- Agricultural and Biological Sciences(all)
- Computational Theory and Mathematics