West Nile virus infection in reindeer (Rangifer tarandus)

Mitchell V. Palmer, William C. Stoffregen, Douglas G Rogers, Amir N. Hamir, Juergen A. Richt, Douglas D. Pedersen, W. Ray Waters

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

West Nile virus (WNV) infection in 4 reindeer (Rangifer tarandus) resulted in lymphohistiocytic encephalomyelitis within the medulla oblongata and cervical spinal cord. Immunohistochemistry revealed WNV antigen within neurons and among mononuclear cell infiltrates. These represent the first known cases of clinical WNV infection in Cervidae. Clinical signs and lesions were similar to those described in horses. Nucleotide sequence of a 768-bp region of the WNV E-glycoprotein gene revealed 1 nucleotide mutation, which resulted in a single amino acid substitution from a serine to a glycine (position 227 of E-glycoprotein) when compared with the prototype WNV-NY99 strain (isolated from Bronx zoo flamingo 382-99).

Original languageEnglish (US)
Pages (from-to)219-222
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Volume16
Issue number3
DOIs
StatePublished - Jan 1 2004

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Reindeer
West Nile virus
Rangifer tarandus
reindeer
Virus Diseases
infection
glycoproteins
Glycoproteins
Cervidae
medulla oblongata
Encephalomyelitis
Phoenicopteridae
Medulla Oblongata
amino acid substitution
Amino Acid Substitution
encephalitis
zoos
glycine (amino acid)
prototypes
spinal cord

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Palmer, M. V., Stoffregen, W. C., Rogers, D. G., Hamir, A. N., Richt, J. A., Pedersen, D. D., & Waters, W. R. (2004). West Nile virus infection in reindeer (Rangifer tarandus). Journal of Veterinary Diagnostic Investigation, 16(3), 219-222. https://doi.org/10.1177/104063870401600307

West Nile virus infection in reindeer (Rangifer tarandus). / Palmer, Mitchell V.; Stoffregen, William C.; Rogers, Douglas G; Hamir, Amir N.; Richt, Juergen A.; Pedersen, Douglas D.; Waters, W. Ray.

In: Journal of Veterinary Diagnostic Investigation, Vol. 16, No. 3, 01.01.2004, p. 219-222.

Research output: Contribution to journalArticle

Palmer, MV, Stoffregen, WC, Rogers, DG, Hamir, AN, Richt, JA, Pedersen, DD & Waters, WR 2004, 'West Nile virus infection in reindeer (Rangifer tarandus)', Journal of Veterinary Diagnostic Investigation, vol. 16, no. 3, pp. 219-222. https://doi.org/10.1177/104063870401600307
Palmer MV, Stoffregen WC, Rogers DG, Hamir AN, Richt JA, Pedersen DD et al. West Nile virus infection in reindeer (Rangifer tarandus). Journal of Veterinary Diagnostic Investigation. 2004 Jan 1;16(3):219-222. https://doi.org/10.1177/104063870401600307
Palmer, Mitchell V. ; Stoffregen, William C. ; Rogers, Douglas G ; Hamir, Amir N. ; Richt, Juergen A. ; Pedersen, Douglas D. ; Waters, W. Ray. / West Nile virus infection in reindeer (Rangifer tarandus). In: Journal of Veterinary Diagnostic Investigation. 2004 ; Vol. 16, No. 3. pp. 219-222.
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