Weaning and discontinuation of epoprostenol in children with idiopathic pulmonary arterial hypertension receiving concomitant bosentan

D. Dunbar Ivy, Aimee Doran, Lori Claussen, Deborah Bingaman, Angela T Yetman

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

In 7 of 8 children with idiopathic pulmonary arterial hypertension treated with intravenous epoprostenol for >1 year, concomitant use of bosentan allowed a reduction of epoprostenol and decreased its associated side effects without deterioration of clinical and hemodynamic parameters. In 3 children with normal or near-normal pulmonary artery pressure on epoprostenol, the addition of bosentan allowed discontinuation of epoprostenol and stabilization of hemodynamics for up to 1 year.

Original languageEnglish (US)
Pages (from-to)943-946
Number of pages4
JournalAmerican Journal of Cardiology
Volume93
Issue number7
DOIs
StatePublished - Apr 1 2004

Fingerprint

Epoprostenol
Weaning
Hemodynamics
Pulmonary Artery
Pressure
bosentan
Familial Primary Pulmonary Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Weaning and discontinuation of epoprostenol in children with idiopathic pulmonary arterial hypertension receiving concomitant bosentan. / Ivy, D. Dunbar; Doran, Aimee; Claussen, Lori; Bingaman, Deborah; Yetman, Angela T.

In: American Journal of Cardiology, Vol. 93, No. 7, 01.04.2004, p. 943-946.

Research output: Contribution to journalArticle

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