Vitamin D supplementation may improve symptoms in Meniere's disease

Bela Büki, Heinz Jünger, Yunxia W Lundberg

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin. According to their hypothesis, vitamin D supplementation may indeed have a beneficial effect in Meniere's disease if the symptoms are caused by a local postviral autoimmune reaction. Vitamin D has a strong immunomodulatory role, one of which is the regulation of the expression of pro-inflammatory mediators. The authors suggest further epidemiological studies to decide if there is a connection between vitamin D deficiency and Meniere's disease.

Original languageEnglish (US)
Pages (from-to)44-46
Number of pages3
JournalMedical Hypotheses
Volume116
DOIs
StatePublished - Jul 2018

Fingerprint

Meniere Disease
Vitamin D
Vitamin D Deficiency
Deficiency Diseases
Gentamicins
Epidemiologic Studies
Therapeutics

Keywords

  • Deficiency
  • Meniere's disease
  • Vitamin D

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vitamin D supplementation may improve symptoms in Meniere's disease. / Büki, Bela; Jünger, Heinz; Lundberg, Yunxia W.

In: Medical Hypotheses, Vol. 116, 07.2018, p. 44-46.

Research output: Contribution to journalArticle

@article{b897a905af0a4a1db05ea3746f8768e8,
title = "Vitamin D supplementation may improve symptoms in Meniere's disease",
abstract = "In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin. According to their hypothesis, vitamin D supplementation may indeed have a beneficial effect in Meniere's disease if the symptoms are caused by a local postviral autoimmune reaction. Vitamin D has a strong immunomodulatory role, one of which is the regulation of the expression of pro-inflammatory mediators. The authors suggest further epidemiological studies to decide if there is a connection between vitamin D deficiency and Meniere's disease.",
keywords = "Deficiency, Meniere's disease, Vitamin D",
author = "Bela B{\"u}ki and Heinz J{\"u}nger and Lundberg, {Yunxia W}",
year = "2018",
month = "7",
doi = "10.1016/j.mehy.2018.04.019",
language = "English (US)",
volume = "116",
pages = "44--46",
journal = "Medical Hypotheses",
issn = "0306-9877",
publisher = "Churchill Livingstone",

}

TY - JOUR

T1 - Vitamin D supplementation may improve symptoms in Meniere's disease

AU - Büki, Bela

AU - Jünger, Heinz

AU - Lundberg, Yunxia W

PY - 2018/7

Y1 - 2018/7

N2 - In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin. According to their hypothesis, vitamin D supplementation may indeed have a beneficial effect in Meniere's disease if the symptoms are caused by a local postviral autoimmune reaction. Vitamin D has a strong immunomodulatory role, one of which is the regulation of the expression of pro-inflammatory mediators. The authors suggest further epidemiological studies to decide if there is a connection between vitamin D deficiency and Meniere's disease.

AB - In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin. According to their hypothesis, vitamin D supplementation may indeed have a beneficial effect in Meniere's disease if the symptoms are caused by a local postviral autoimmune reaction. Vitamin D has a strong immunomodulatory role, one of which is the regulation of the expression of pro-inflammatory mediators. The authors suggest further epidemiological studies to decide if there is a connection between vitamin D deficiency and Meniere's disease.

KW - Deficiency

KW - Meniere's disease

KW - Vitamin D

UR - http://www.scopus.com/inward/record.url?scp=85046072946&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85046072946&partnerID=8YFLogxK

U2 - 10.1016/j.mehy.2018.04.019

DO - 10.1016/j.mehy.2018.04.019

M3 - Article

C2 - 29857909

AN - SCOPUS:85046072946

VL - 116

SP - 44

EP - 46

JO - Medical Hypotheses

JF - Medical Hypotheses

SN - 0306-9877

ER -