Vitamin D supplementation: A potential booster for urticaria therapy

Andy Rorie, Jill A. Poole

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Chronic urticaria is a common skin condition whereby the etiology remains largely idiopathic and the mainstay therapy is symptomatic control with antihistamines. There have been a limited number of small studies suggesting a potential role for vitamin D in chronic urticaria, and this this editorial review will discuss the current supporting evidence. Associations for decreased serum vitamin 25 hydroxyvitamin D levels in subjects with chronic urticaria have been reported. In addition to observational reports, there has been a randomized, prospective, blinded trial demonstrating symptom improvement when high vitamin D3 supplementation was utilized as an add-on therapy for urticarial management. More research is needed to address mechanisms of action and to investigate vitamin D supplementation in larger and longer duration human trials.

Original languageEnglish (US)
Pages (from-to)1269-1271
Number of pages3
JournalExpert Review of Clinical Immunology
Volume10
Issue number10
DOIs
Publication statusPublished - Oct 1 2014

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Keywords

  • chronic
  • mechanism
  • review
  • supplementation
  • therapy
  • urticaria
  • vitamin D

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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