Viral encephalitis

Clinton Jones, Eric M. Scholar

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Encephalitis is an acute inflammation of the brain that is caused by a viral infection. Several viruses, herpes simplex virus type 1 (HSV-1), Varicella zoster virus (VZV), cytomegalovirus (CMV), West Nile virus, and certain members of the Flavivirus family or Bunyavirus genus for example, can cause encephalitis. Although these viruses have very different biological properties, they have the ability to enter the central nervous system, replicated in neurons, and can all cause encephalitis. In general, patients with encephalitis suffer from fever, headache, seizures, and photophobia. Less commonly, stiffness of the neck can occur with rare cases of patients also suffering from stiffness of the limbs, slowness in movement and clumsiness depending on which part of the brain is involved. Encephalitis is not a typical outcome of viral infections, but it is life threatening and difficult to treat. This chapter discusses the properties of the viruses that cause encephalitis, how they cause clinical disease, and the available therapeutic strategies that are available.

Original languageEnglish (US)
Title of host publicationNeuroimmune Pharmacology
PublisherSpringer US
Pages327-341
Number of pages15
ISBN (Print)9780387725727
DOIs
StatePublished - Dec 1 2008

Fingerprint

Viral Encephalitis
Encephalitis
Virus Diseases
Orthobunyavirus
Encephalitis Viruses
Viruses
Flavivirus
West Nile virus
Photophobia
Febrile Seizures
Human Herpesvirus 3
Aptitude
Human Herpesvirus 1
Cytomegalovirus
Headache
Neck
Extremities
Central Nervous System
Neurons
Brain

Keywords

  • Acyclovir
  • Cidofovir
  • Cytomegalovirus
  • Encephalitis
  • Famciclovir
  • Foscarnet
  • Ganciclovir
  • Herpes simplex virus type 1
  • Latencyneurological disorders
  • Lifecycle
  • Valacyclovir
  • Varicella zoster virus
  • West Nile virus

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Jones, C., & Scholar, E. M. (2008). Viral encephalitis. In Neuroimmune Pharmacology (pp. 327-341). Springer US. https://doi.org/10.1007/978-0-387-72573-4_24

Viral encephalitis. / Jones, Clinton; Scholar, Eric M.

Neuroimmune Pharmacology. Springer US, 2008. p. 327-341.

Research output: Chapter in Book/Report/Conference proceedingChapter

Jones, C & Scholar, EM 2008, Viral encephalitis. in Neuroimmune Pharmacology. Springer US, pp. 327-341. https://doi.org/10.1007/978-0-387-72573-4_24
Jones C, Scholar EM. Viral encephalitis. In Neuroimmune Pharmacology. Springer US. 2008. p. 327-341 https://doi.org/10.1007/978-0-387-72573-4_24
Jones, Clinton ; Scholar, Eric M. / Viral encephalitis. Neuroimmune Pharmacology. Springer US, 2008. pp. 327-341
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