Vimentin expression in human squamous carcinoma cells

Relationship with phenotypic changes and cadherin-based cell adhesion

Shahidul Islam, Jae Beom Kim, Jill Trendel, Margaret J. Wheelock, Keith R Johnson

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Phenotypic changes resembling an epithelial-to-mesenchymal transition often occur as epithelial cells become tumorigenic. Two proteins that have been implicated in this process are vimentin and N-cadherin. In this study, we sought to establish a link between expression of vimentin and N-cadherin as oral squamous epithelial cells undergo a morphologic change resembling an epithelial-to-mesenchymal transition. We found that N-cadherin and vimentin did not influence the expression of one another. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)141-150
Number of pages10
JournalJournal of Cellular Biochemistry
Volume78
Issue number1
DOIs
StatePublished - Jun 22 2000

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Cell adhesion
Vimentin
Cadherins
Cell Adhesion
Squamous Cell Carcinoma
Epithelial-Mesenchymal Transition
Epithelial Cells
Proteins

Keywords

  • Epithelial to mesenchymal transition
  • N-cadherin
  • Squamous cell carcinoma
  • Vimentin

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Vimentin expression in human squamous carcinoma cells : Relationship with phenotypic changes and cadherin-based cell adhesion. / Islam, Shahidul; Kim, Jae Beom; Trendel, Jill; Wheelock, Margaret J.; Johnson, Keith R.

In: Journal of Cellular Biochemistry, Vol. 78, No. 1, 22.06.2000, p. 141-150.

Research output: Contribution to journalArticle

Islam, Shahidul ; Kim, Jae Beom ; Trendel, Jill ; Wheelock, Margaret J. ; Johnson, Keith R. / Vimentin expression in human squamous carcinoma cells : Relationship with phenotypic changes and cadherin-based cell adhesion. In: Journal of Cellular Biochemistry. 2000 ; Vol. 78, No. 1. pp. 141-150.
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