Vapor, dust, and smoke exposure in relation to adult-onset asthma and chronic respiratory symptoms

The Singapore Chinese Health Study

Tricia D LeVan, Woon Puay Koh, Hin Peng Lee, David Koh, Mimi C. Yu, Stephanie J. London

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Occupational factors contribute to a significant fraction of respiratory disease and symptoms. The authors evaluated the role of occupational exposures in asthma, chronic bronchitis, and respiratory symptoms in the Singapore Chinese Health Study, a population-based cohort of adults aged 45-74 years at enrollment in 1993-1998. Information on occupations and occupational exposures was collected at enrollment for 52,325 subjects for whom respiratory outcomes were obtained via follow-up interviews in 1999-2004. Exposure to dusts from cotton, wood, metal, minerals, and/or asbestos was associated with nonchronic cough and/or phlegm (odds ratio (OR) = 1.19, 95% confidence interval (CI): 1.08, 1.30), chronic bronchitis (OR = 1.26, 95% CI: 1.01, 1.57), and adult-onset asthma (OR = 1.14, 95% CI: 1.00, 1.30). Cotton dust was the major contributor to respiratory symptoms. Vapor exposure from chemical solvents, dyes, cooling oils, paints, wood preservatives, and/or pesticides was associated with nonchronic cough or phlegm (OR = 1.14, 95% CI: 1.03, 1.27), chronic dry cough (OR = 1.55, 95% CI: 1.19, 2.01), and adult-onset asthma (OR = 1.34, 95% CI: 1.15, 1.56). Chemical solvents, cooling oils, and pesticides were the major contributors to respiratory symptoms. These data support the role of occupational exposures in the etiology of respiratory illness in a population-based cohort in Singapore with a low prevalence of atopic illness.

Original languageEnglish (US)
Pages (from-to)1118-1128
Number of pages11
JournalAmerican Journal of Epidemiology
Volume163
Issue number12
DOIs
StatePublished - Jun 1 2006

Fingerprint

Singapore
Dust
Smoke
Asthma
Odds Ratio
Confidence Intervals
Health
Occupational Exposure
Cough
Chronic Bronchitis
Pesticides
Oils
Paint
Asbestos
Occupations
Population
Minerals
Coloring Agents
Metals
Interviews

Keywords

  • Asthma
  • Bronchitis, chronic
  • Occupational diseases
  • Occupational exposure
  • Pulmonary disease, chronic obstructive

ASJC Scopus subject areas

  • Epidemiology

Cite this

Vapor, dust, and smoke exposure in relation to adult-onset asthma and chronic respiratory symptoms : The Singapore Chinese Health Study. / LeVan, Tricia D; Koh, Woon Puay; Lee, Hin Peng; Koh, David; Yu, Mimi C.; London, Stephanie J.

In: American Journal of Epidemiology, Vol. 163, No. 12, 01.06.2006, p. 1118-1128.

Research output: Contribution to journalArticle

LeVan, Tricia D ; Koh, Woon Puay ; Lee, Hin Peng ; Koh, David ; Yu, Mimi C. ; London, Stephanie J. / Vapor, dust, and smoke exposure in relation to adult-onset asthma and chronic respiratory symptoms : The Singapore Chinese Health Study. In: American Journal of Epidemiology. 2006 ; Vol. 163, No. 12. pp. 1118-1128.
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