La leucoencéphalopathie vacuolaire induite par l'héroïne: 4 Cas

Translated title of the contribution: Vacuolar leucoencephalopathy induced by heroin: 4 Cases

S. Koussa, R. Zabad, T. Rizk, J. Tamraz, R. Nasnas, R. Chemaly

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We report 4 cases of toxic leucoencephalopathy after heroin inhalation. The clinical features, which usually occur some days or even longer after the last heroin consumption, are dominated by a cerebellar syndrome. The cerebellar hemispheres are almost always affected; the cerebral hemispheres, the cerebellar peduncles and the pyramidal tract may be affected. Vacuolar demyelination is the morphological substract of the lesions, which are symmmetrical, not contrast enhancing, hypodense on CT scan and hyperintense on T2-weighted MRI. The pathophysiology is unknown and seems different from post-anoxic leucoencephalopathy. The disease is usually progressive leading sometimes to death, but some cases show slow recovery.

Original languageFrench
Pages (from-to)177-182
Number of pages6
JournalRevue Neurologique
Volume158
Issue number2
StatePublished - Mar 19 2002

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Leukoencephalopathies
Heroin
Cerebellar Diseases
Pyramidal Tracts
Poisons
Cerebrum
Demyelinating Diseases
Inhalation

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Koussa, S., Zabad, R., Rizk, T., Tamraz, J., Nasnas, R., & Chemaly, R. (2002). La leucoencéphalopathie vacuolaire induite par l'héroïne: 4 Cas. Revue Neurologique, 158(2), 177-182.

La leucoencéphalopathie vacuolaire induite par l'héroïne : 4 Cas. / Koussa, S.; Zabad, R.; Rizk, T.; Tamraz, J.; Nasnas, R.; Chemaly, R.

In: Revue Neurologique, Vol. 158, No. 2, 19.03.2002, p. 177-182.

Research output: Contribution to journalArticle

Koussa, S, Zabad, R, Rizk, T, Tamraz, J, Nasnas, R & Chemaly, R 2002, 'La leucoencéphalopathie vacuolaire induite par l'héroïne: 4 Cas', Revue Neurologique, vol. 158, no. 2, pp. 177-182.
Koussa S, Zabad R, Rizk T, Tamraz J, Nasnas R, Chemaly R. La leucoencéphalopathie vacuolaire induite par l'héroïne: 4 Cas. Revue Neurologique. 2002 Mar 19;158(2):177-182.
Koussa, S. ; Zabad, R. ; Rizk, T. ; Tamraz, J. ; Nasnas, R. ; Chemaly, R. / La leucoencéphalopathie vacuolaire induite par l'héroïne : 4 Cas. In: Revue Neurologique. 2002 ; Vol. 158, No. 2. pp. 177-182.
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