Using weighted power mean for equivalent square estimation

Sumin Zhou, Qiuwen Wu, Xiaobo Li, Rongtao Ma, Dandan Zheng, Shuo Wang, Mutian Zhang, Sicong Li, Yu Lei, Qiyong Fan, Megan A Hyun, Tyler Diener, Charles Arthur Enke

Research output: Contribution to journalArticle

Abstract

Purpose: Equivalent Square (ES) enables the calculation of many radiation quantities for rectangular treatment fields, based only on measurements from square fields. While it is widely applied in radiotherapy, its accuracy, especially for extremely elongated fields, still leaves room for improvement. In this study, we introduce a novel explicit ES formula based on Weighted Power Mean (WPM) function and compare its performance with the Sterling formula and Vadash/Bjärngard's formula. Methods: The proposed WPM formula is ESWPMa,b=waα+1-wbα1/α for a rectangular photon field with sides a and b. The formula performance was evaluated by three methods: standard deviation of model fitting residual error, maximum relative model prediction error, and model's Akaike Information Criterion (AIC). Testing datasets included the ES table from British Journal of Radiology (BJR), photon output factors (Scp) from the Varian TrueBeam Representative Beam Data (Med Phys. 2012;39:6981-7018), and published Scp data for Varian TrueBeam Edge (J Appl Clin Med Phys. 2015;16:125-148). Results: For the BJR dataset, the best-fit parameter value α = -1.25 achieved a 20% reduction in standard deviation in ES estimation residual error compared with the two established formulae. For the two Varian datasets, employing WPM reduced the maximum relative error from 3.5% (Sterling) or 2% (Vadash/Bjärngard) to 0.7% for open field sizes ranging from 3 cm to 40 cm, and the reduction was even more prominent for 1 cm field sizes on Edge (J Appl Clin Med Phys. 2015;16:125-148). The AIC value of the WPM formula was consistently lower than its counterparts from the traditional formulae on photon output factors, most prominent on very elongated small fields. Conclusion: The WPM formula outperformed the traditional formulae on three testing datasets. With increasing utilization of very elongated, small rectangular fields in modern radiotherapy, improved photon output factor estimation is expected by adopting the WPM formula in treatment planning and secondary MU check.

Original languageEnglish (US)
Pages (from-to)194-199
Number of pages6
JournalJournal of Applied Clinical Medical Physics
Volume18
Issue number6
DOIs
StatePublished - Nov 1 2017

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Keywords

  • Akaike Information Criterion
  • Equivalent square
  • Linac output factors
  • Weighted power mean

ASJC Scopus subject areas

  • Radiation
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

Cite this

Using weighted power mean for equivalent square estimation. / Zhou, Sumin; Wu, Qiuwen; Li, Xiaobo; Ma, Rongtao; Zheng, Dandan; Wang, Shuo; Zhang, Mutian; Li, Sicong; Lei, Yu; Fan, Qiyong; Hyun, Megan A; Diener, Tyler; Enke, Charles Arthur.

In: Journal of Applied Clinical Medical Physics, Vol. 18, No. 6, 01.11.2017, p. 194-199.

Research output: Contribution to journalArticle

Zhou, Sumin ; Wu, Qiuwen ; Li, Xiaobo ; Ma, Rongtao ; Zheng, Dandan ; Wang, Shuo ; Zhang, Mutian ; Li, Sicong ; Lei, Yu ; Fan, Qiyong ; Hyun, Megan A ; Diener, Tyler ; Enke, Charles Arthur. / Using weighted power mean for equivalent square estimation. In: Journal of Applied Clinical Medical Physics. 2017 ; Vol. 18, No. 6. pp. 194-199.
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abstract = "Purpose: Equivalent Square (ES) enables the calculation of many radiation quantities for rectangular treatment fields, based only on measurements from square fields. While it is widely applied in radiotherapy, its accuracy, especially for extremely elongated fields, still leaves room for improvement. In this study, we introduce a novel explicit ES formula based on Weighted Power Mean (WPM) function and compare its performance with the Sterling formula and Vadash/Bj{\"a}rngard's formula. Methods: The proposed WPM formula is ESWPMa,b=waα+1-wbα1/α for a rectangular photon field with sides a and b. The formula performance was evaluated by three methods: standard deviation of model fitting residual error, maximum relative model prediction error, and model's Akaike Information Criterion (AIC). Testing datasets included the ES table from British Journal of Radiology (BJR), photon output factors (Scp) from the Varian TrueBeam Representative Beam Data (Med Phys. 2012;39:6981-7018), and published Scp data for Varian TrueBeam Edge (J Appl Clin Med Phys. 2015;16:125-148). Results: For the BJR dataset, the best-fit parameter value α = -1.25 achieved a 20{\%} reduction in standard deviation in ES estimation residual error compared with the two established formulae. For the two Varian datasets, employing WPM reduced the maximum relative error from 3.5{\%} (Sterling) or 2{\%} (Vadash/Bj{\"a}rngard) to 0.7{\%} for open field sizes ranging from 3 cm to 40 cm, and the reduction was even more prominent for 1 cm field sizes on Edge (J Appl Clin Med Phys. 2015;16:125-148). The AIC value of the WPM formula was consistently lower than its counterparts from the traditional formulae on photon output factors, most prominent on very elongated small fields. Conclusion: The WPM formula outperformed the traditional formulae on three testing datasets. With increasing utilization of very elongated, small rectangular fields in modern radiotherapy, improved photon output factor estimation is expected by adopting the WPM formula in treatment planning and secondary MU check.",
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AU - Li, Xiaobo

AU - Ma, Rongtao

AU - Zheng, Dandan

AU - Wang, Shuo

AU - Zhang, Mutian

AU - Li, Sicong

AU - Lei, Yu

AU - Fan, Qiyong

AU - Hyun, Megan A

AU - Diener, Tyler

AU - Enke, Charles Arthur

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