Use of disodium pamidronate in children with hypercalcemia awaiting liver transplantation

Thomas M. Attard, Anil Dhawan, Stuart S. Kaufman, Dean S Collier, Alan Norman Langnas

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

We report four children with advanced liver disease awaiting liver transplantation who developed moderately severe hypercalcemia (range: 1.65-2.40 mmol/L) while receiving total parenteral nutrition. Hypercalcemia had been unresponsive to cessation of calcium intake and therapy with loop diuretics and calcitonin. One or two intravenous doses of disodium pamidronate (35-50 mg/m2) resulted in normalization of plasma calcium concentration within 2-4 d in all four children. Pamidronate may be useful for children with hypercalcemia associated with liver disease.

Original languageEnglish (US)
Pages (from-to)157-159
Number of pages3
JournalPediatric Transplantation
Volume2
Issue number2
Publication statusPublished - Dec 1 1998

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Keywords

  • Bisphospnonate pamidronate
  • Child
  • Hypercalcemia
  • Liver transplantation
  • Short bowel syndrome
  • Total parenteral nutrition

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

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