Urinary and plasma gonadotropin concentrations in golden lion tamarins (Leontopithecus r. rosalia)

Jeffrey A. French, William A. deGraw, Shelton E. Hendricks, Fritz Wegner, William E. Bridson

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This paper describes the development and validation of a plasma and urinary gonadotropin immunoassay for golden lion tamarins (Leontopithecus rosalia), an endangered New World callitrichid primate. The assay is derived from a macaque chorionic gonadotropin assay and was validated for both plasma and urine samples in L. rosalia. Levels of immunoreactive LH/CG in lion tamarin urine were highly correlated (r = + 0.98) with gonadotropin bioactivity. Immunoreactive LH/CG levels were examined in two contexts: in the urine of adult females and in the plasma of adult males after administration of estrogen. Peaks of gonadotropin excretion were detected in samples collected from nonpregnant adult females. The peaks occurred immediately prior to cyclic elevations in urinary estrogen excretion. Plasma LH/CG concentration in males measured 24 and 48 hours after a single 50 μg injection of estradiol benzoate were significantly lower than levels at these time points measured after control treatment. Together, the results of this study point to the utility of the gonadotropin assay for monitoring reproductive function in both female and male lion tamarins.

Original languageEnglish (US)
Pages (from-to)53-59
Number of pages7
JournalAmerican Journal of Primatology
Volume26
Issue number1
DOIs
StatePublished - 1992

Fingerprint

Leontopithecus rosalia
gonadotropins
Leontopithecus
urine
plasma
assay
excretion
estrogens
assays
chorionic gonadotropins
bioactivity
immunoassay
benzoates
immunoassays
Macaca
primate
estradiol
Primates
injection
sampling

Keywords

  • luteinizing hormone
  • negative feedback
  • ovulation detection
  • tamarin reproduction
  • urinary hormones

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Animal Science and Zoology

Cite this

Urinary and plasma gonadotropin concentrations in golden lion tamarins (Leontopithecus r. rosalia). / French, Jeffrey A.; deGraw, William A.; Hendricks, Shelton E.; Wegner, Fritz; Bridson, William E.

In: American Journal of Primatology, Vol. 26, No. 1, 1992, p. 53-59.

Research output: Contribution to journalArticle

French, Jeffrey A. ; deGraw, William A. ; Hendricks, Shelton E. ; Wegner, Fritz ; Bridson, William E. / Urinary and plasma gonadotropin concentrations in golden lion tamarins (Leontopithecus r. rosalia). In: American Journal of Primatology. 1992 ; Vol. 26, No. 1. pp. 53-59.
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