Undifferentiated embryonal sarcoma of liver

Avyakta Kallam, Jairam Krishnamurthy, Jessica Kozel, Nicole A Shonka

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Undifferentiated embryonal sarcoma of the liver (UESL) is a rare malignant hepatic tumor. A 47 year old male presented with symptoms of sour taste in his mouth, occasional nausea, indigestion and 15-pound weight loss over two months. He had an unremarkable upper gastrointestinal endoscopy. Imaging showed a large liver mass in the left hepatic lobe that was resected and then reported as UESL. He went on to develop lung metastases and was initially treated with doxorubicin and ifosfamide followed by switching of therapy to gemcitabine and docetaxel due to progression of disease. He had a good response after two cycles and went on to receive four more cycles, achieving stable disease. We can therefore conclude that the combination of gemcitabine and docetaxel is a potential therapeutic option for patients with UESL.

Original languageEnglish (US)
Article number6009
Pages (from-to)130-132
Number of pages3
JournalRare Tumors
Volume7
Issue number4
DOIs
StatePublished - Dec 30 2015

Fingerprint

Sarcoma
docetaxel
gemcitabine
Liver
Ifosfamide
Gastrointestinal Endoscopy
Dyspepsia
Doxorubicin
Nausea
Mouth
Disease Progression
Weight Loss
Neoplasm Metastasis
Lung
Therapeutics
Neoplasms

Keywords

  • Embryonal
  • Liver
  • Sarcoma

ASJC Scopus subject areas

  • Histology
  • Oncology

Cite this

Undifferentiated embryonal sarcoma of liver. / Kallam, Avyakta; Krishnamurthy, Jairam; Kozel, Jessica; Shonka, Nicole A.

In: Rare Tumors, Vol. 7, No. 4, 6009, 30.12.2015, p. 130-132.

Research output: Contribution to journalArticle

Kallam, A, Krishnamurthy, J, Kozel, J & Shonka, NA 2015, 'Undifferentiated embryonal sarcoma of liver', Rare Tumors, vol. 7, no. 4, 6009, pp. 130-132. https://doi.org/10.4081/rt.2015.6009
Kallam, Avyakta ; Krishnamurthy, Jairam ; Kozel, Jessica ; Shonka, Nicole A. / Undifferentiated embryonal sarcoma of liver. In: Rare Tumors. 2015 ; Vol. 7, No. 4. pp. 130-132.
@article{f8d9209736b1444a9389f4e56d000243,
title = "Undifferentiated embryonal sarcoma of liver",
abstract = "Undifferentiated embryonal sarcoma of the liver (UESL) is a rare malignant hepatic tumor. A 47 year old male presented with symptoms of sour taste in his mouth, occasional nausea, indigestion and 15-pound weight loss over two months. He had an unremarkable upper gastrointestinal endoscopy. Imaging showed a large liver mass in the left hepatic lobe that was resected and then reported as UESL. He went on to develop lung metastases and was initially treated with doxorubicin and ifosfamide followed by switching of therapy to gemcitabine and docetaxel due to progression of disease. He had a good response after two cycles and went on to receive four more cycles, achieving stable disease. We can therefore conclude that the combination of gemcitabine and docetaxel is a potential therapeutic option for patients with UESL.",
keywords = "Embryonal, Liver, Sarcoma",
author = "Avyakta Kallam and Jairam Krishnamurthy and Jessica Kozel and Shonka, {Nicole A}",
year = "2015",
month = "12",
day = "30",
doi = "10.4081/rt.2015.6009",
language = "English (US)",
volume = "7",
pages = "130--132",
journal = "Rare Tumors",
issn = "2036-3605",
publisher = "PagePress",
number = "4",

}

TY - JOUR

T1 - Undifferentiated embryonal sarcoma of liver

AU - Kallam, Avyakta

AU - Krishnamurthy, Jairam

AU - Kozel, Jessica

AU - Shonka, Nicole A

PY - 2015/12/30

Y1 - 2015/12/30

N2 - Undifferentiated embryonal sarcoma of the liver (UESL) is a rare malignant hepatic tumor. A 47 year old male presented with symptoms of sour taste in his mouth, occasional nausea, indigestion and 15-pound weight loss over two months. He had an unremarkable upper gastrointestinal endoscopy. Imaging showed a large liver mass in the left hepatic lobe that was resected and then reported as UESL. He went on to develop lung metastases and was initially treated with doxorubicin and ifosfamide followed by switching of therapy to gemcitabine and docetaxel due to progression of disease. He had a good response after two cycles and went on to receive four more cycles, achieving stable disease. We can therefore conclude that the combination of gemcitabine and docetaxel is a potential therapeutic option for patients with UESL.

AB - Undifferentiated embryonal sarcoma of the liver (UESL) is a rare malignant hepatic tumor. A 47 year old male presented with symptoms of sour taste in his mouth, occasional nausea, indigestion and 15-pound weight loss over two months. He had an unremarkable upper gastrointestinal endoscopy. Imaging showed a large liver mass in the left hepatic lobe that was resected and then reported as UESL. He went on to develop lung metastases and was initially treated with doxorubicin and ifosfamide followed by switching of therapy to gemcitabine and docetaxel due to progression of disease. He had a good response after two cycles and went on to receive four more cycles, achieving stable disease. We can therefore conclude that the combination of gemcitabine and docetaxel is a potential therapeutic option for patients with UESL.

KW - Embryonal

KW - Liver

KW - Sarcoma

UR - http://www.scopus.com/inward/record.url?scp=84954470790&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954470790&partnerID=8YFLogxK

U2 - 10.4081/rt.2015.6009

DO - 10.4081/rt.2015.6009

M3 - Article

C2 - 26788276

AN - SCOPUS:84954470790

VL - 7

SP - 130

EP - 132

JO - Rare Tumors

JF - Rare Tumors

SN - 2036-3605

IS - 4

M1 - 6009

ER -