Tularemia: Retrospective review of 10 years' experience in Arkansas

Jessica Snowden, Stephanie Stovall

Research output: Contribution to journalReview article

28 Citations (Scopus)

Abstract

Purpose: The purpose of this study is to review all cases of tularemia, a tick-borne illness, among inpatients at Arkansas Children's Hospital (ACH) from 1996-2006 to discuss clinical presentation, diagnosis and treatment. Records of the Infectious Disease Section were reviewed to identify cases of suspected or proven tularemia. Results: Seventeen patients presented with ulceroglandular tularemia and thirteen with glandular disease. Most patients had been ill for 10-14 days prior to admission and were evaluated at least once by another physician. Serology was positive in 77% of patients, including several positive on convalescent testing alone. Most patients responded well to treatment with gentamicin. Conclusions: This series emphasizes the importance of tularemia as an early consideration among children with fever and lymphadenopathy in Arkansas. Convalescent serology is an important tool, as many patients will remain seronegative early in illness. Gentamicin remains effective treatment and should be considered first-line therapy for suspected tularemia.

Original languageEnglish (US)
Pages (from-to)64-68
Number of pages5
JournalClinical pediatrics
Volume50
Issue number1
DOIs
StatePublished - Jan 1 2011

Fingerprint

Tularemia
Serology
Gentamicins
Ticks
Therapeutics
Communicable Diseases
Inpatients
Fever
Physicians

Keywords

  • general pediatrics
  • infectious diseases

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Tularemia : Retrospective review of 10 years' experience in Arkansas. / Snowden, Jessica; Stovall, Stephanie.

In: Clinical pediatrics, Vol. 50, No. 1, 01.01.2011, p. 64-68.

Research output: Contribution to journalReview article

@article{8d2f2ca6b1364658861228c9361bce2f,
title = "Tularemia: Retrospective review of 10 years' experience in Arkansas",
abstract = "Purpose: The purpose of this study is to review all cases of tularemia, a tick-borne illness, among inpatients at Arkansas Children's Hospital (ACH) from 1996-2006 to discuss clinical presentation, diagnosis and treatment. Records of the Infectious Disease Section were reviewed to identify cases of suspected or proven tularemia. Results: Seventeen patients presented with ulceroglandular tularemia and thirteen with glandular disease. Most patients had been ill for 10-14 days prior to admission and were evaluated at least once by another physician. Serology was positive in 77{\%} of patients, including several positive on convalescent testing alone. Most patients responded well to treatment with gentamicin. Conclusions: This series emphasizes the importance of tularemia as an early consideration among children with fever and lymphadenopathy in Arkansas. Convalescent serology is an important tool, as many patients will remain seronegative early in illness. Gentamicin remains effective treatment and should be considered first-line therapy for suspected tularemia.",
keywords = "general pediatrics, infectious diseases",
author = "Jessica Snowden and Stephanie Stovall",
year = "2011",
month = "1",
day = "1",
doi = "10.1177/0009922810381425",
language = "English (US)",
volume = "50",
pages = "64--68",
journal = "Clinical Pediatrics",
issn = "0009-9228",
publisher = "SAGE Publications Inc.",
number = "1",

}

TY - JOUR

T1 - Tularemia

T2 - Retrospective review of 10 years' experience in Arkansas

AU - Snowden, Jessica

AU - Stovall, Stephanie

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Purpose: The purpose of this study is to review all cases of tularemia, a tick-borne illness, among inpatients at Arkansas Children's Hospital (ACH) from 1996-2006 to discuss clinical presentation, diagnosis and treatment. Records of the Infectious Disease Section were reviewed to identify cases of suspected or proven tularemia. Results: Seventeen patients presented with ulceroglandular tularemia and thirteen with glandular disease. Most patients had been ill for 10-14 days prior to admission and were evaluated at least once by another physician. Serology was positive in 77% of patients, including several positive on convalescent testing alone. Most patients responded well to treatment with gentamicin. Conclusions: This series emphasizes the importance of tularemia as an early consideration among children with fever and lymphadenopathy in Arkansas. Convalescent serology is an important tool, as many patients will remain seronegative early in illness. Gentamicin remains effective treatment and should be considered first-line therapy for suspected tularemia.

AB - Purpose: The purpose of this study is to review all cases of tularemia, a tick-borne illness, among inpatients at Arkansas Children's Hospital (ACH) from 1996-2006 to discuss clinical presentation, diagnosis and treatment. Records of the Infectious Disease Section were reviewed to identify cases of suspected or proven tularemia. Results: Seventeen patients presented with ulceroglandular tularemia and thirteen with glandular disease. Most patients had been ill for 10-14 days prior to admission and were evaluated at least once by another physician. Serology was positive in 77% of patients, including several positive on convalescent testing alone. Most patients responded well to treatment with gentamicin. Conclusions: This series emphasizes the importance of tularemia as an early consideration among children with fever and lymphadenopathy in Arkansas. Convalescent serology is an important tool, as many patients will remain seronegative early in illness. Gentamicin remains effective treatment and should be considered first-line therapy for suspected tularemia.

KW - general pediatrics

KW - infectious diseases

UR - http://www.scopus.com/inward/record.url?scp=78650224986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650224986&partnerID=8YFLogxK

U2 - 10.1177/0009922810381425

DO - 10.1177/0009922810381425

M3 - Review article

C2 - 20837613

AN - SCOPUS:78650224986

VL - 50

SP - 64

EP - 68

JO - Clinical Pediatrics

JF - Clinical Pediatrics

SN - 0009-9228

IS - 1

ER -