Triple therapy with methotrexate, sulfasalazine, and hydroxychloroquine in patients with rheumatoid arthritis

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28 Scopus citations


Combinations of DMARDs are currently used to treat rheumatoid arthritis by almost all rheumatologists. This article reviews the published data on the triple combination of methotrexate, sulfasalazine, and hydroxychloroquine, discusses caveats for clinical use, compares efficacy of different combinations, and speculates on future combination therapies.

Original languageEnglish (US)
Pages (from-to)465-477
Number of pages13
JournalRheumatic Disease Clinics of North America
Issue number3
StatePublished - Jan 1 1998


ASJC Scopus subject areas

  • Rheumatology

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