Treatment of stable chronic obstructive pulmonary disease

Stephen I. Rennard

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

Chronic obstructive pulmonary disease (COPD) is a readily diagnosable disorder that responds to treatment. Smoking cessation can reduce symptoms and prevent progression of disease. Bronchodilator therapy is key in improvement of lung function. Three classes of bronchodilators - β agonists, anticholinergics, and theophylline - are available and can be used individually or in combination. Inhaled glucocorticoids can also improve airflow and can be combined with bronchodilators. Inhaled glucocorticoids, in addition, might reduce exacerbation frequency and severity as might some bronchodilators. Effective use of pharmacotherapy in COPD needs integration with a rehabilitation programme and successful treatment of co-morbidities, including depression and anxiety. Treatment for stable COPD can improve the function and quality of life of many patients, could reduce admissions to hospital, and has been suggested to improve survival.

Original languageEnglish (US)
Pages (from-to)791-802
Number of pages12
JournalLancet
Volume364
Issue number9436
DOIs
StatePublished - Aug 28 2004

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Bronchodilator Agents
Chronic Obstructive Pulmonary Disease
Glucocorticoids
Cholinergic Antagonists
Smoking Cessation
Therapeutics
Theophylline
Disease Progression
Rehabilitation
Anxiety
Quality of Life
Depression
Morbidity
Drug Therapy
Lung
Survival

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Treatment of stable chronic obstructive pulmonary disease. / Rennard, Stephen I.

In: Lancet, Vol. 364, No. 9436, 28.08.2004, p. 791-802.

Research output: Contribution to journalArticle

Rennard, Stephen I. / Treatment of stable chronic obstructive pulmonary disease. In: Lancet. 2004 ; Vol. 364, No. 9436. pp. 791-802.
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