Treatment of non-small cell lung cancer in the older patient

Apar Kishor P Ganti, Mollie DeShazo, Alva B. Weir, Arti Hurria

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

Lung cancer is a disease of the elderly, with a median age at diagnosis of 70 years. However, there is a dearth of good quality evidence to guide treatment in this population and most of the data are extrapolated from younger patients. Current research is directed toward establishing simplified instruments to quantify fitness of older patients for various forms of therapy. Although current evidence suggests that outcomes after standard therapy are similar to those seen in younger patients, older patients have an increased incidence of adverse events. Until better predictive markers are available to guide treatment, therapy should be individualized using available instruments, including a comprehensive geriatric assessment. If an older patient is deemed to be fit, it is reasonable to use the treatment options recommended for younger individuals. This article summarizes the available data on the treatment of non-small cell lung cancer in the older patient.

Original languageEnglish (US)
Pages (from-to)230-239
Number of pages10
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume10
Issue number2
DOIs
StatePublished - Feb 1 2012

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Non-Small Cell Lung Carcinoma
Therapeutics
Geriatric Assessment
Lung Neoplasms
Incidence
Research
Population

Keywords

  • Comprehensive geriatric assessment
  • Non-small cell lung cancer
  • Older individuals

ASJC Scopus subject areas

  • Oncology

Cite this

Treatment of non-small cell lung cancer in the older patient. / Ganti, Apar Kishor P; DeShazo, Mollie; Weir, Alva B.; Hurria, Arti.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 10, No. 2, 01.02.2012, p. 230-239.

Research output: Contribution to journalReview article

Ganti, Apar Kishor P ; DeShazo, Mollie ; Weir, Alva B. ; Hurria, Arti. / Treatment of non-small cell lung cancer in the older patient. In: JNCCN Journal of the National Comprehensive Cancer Network. 2012 ; Vol. 10, No. 2. pp. 230-239.
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