Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma)

Kerry Bernal, Marilu Nelson, James R. Neff, Stephen M. Nielsen, Julia A. Bridge

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35 Citations (Scopus)

Abstract

Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man. This finding confirms the nonrandom association of t(2;11)(q31;q12) with collagenous fibroma.

Original languageEnglish (US)
Pages (from-to)161-163
Number of pages3
JournalCancer genetics and cytogenetics
Volume149
Issue number2
DOIs
StatePublished - Mar 1 2004

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Myofibroblasts
Fibroblasts
Neoplasms

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma). / Bernal, Kerry; Nelson, Marilu; Neff, James R.; Nielsen, Stephen M.; Bridge, Julia A.

In: Cancer genetics and cytogenetics, Vol. 149, No. 2, 01.03.2004, p. 161-163.

Research output: Contribution to journalArticle

Bernal, Kerry ; Nelson, Marilu ; Neff, James R. ; Nielsen, Stephen M. ; Bridge, Julia A. / Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma). In: Cancer genetics and cytogenetics. 2004 ; Vol. 149, No. 2. pp. 161-163.
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