Translocation (1;4)(p31;q34) in nonossifying fibroma

Marilu Nelson, Deborah Perry, Glen Ginsburg, Warren G. Sanger, James R. Neff, Julia A. Bridge

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Nonossifying fibroma is a benign, lytic lesion of fibrous origin most often observed in the metaphyseal region of the long bones in children and adolescents. It is frequently asymptomatic and is often characterized by a history of spontaneous resolution. Herein, we report a clinicohistopathologically typical case of nonossifying fibroma arising in the tibia of an 18-year-old skeletally mature female. Conventional cytogenetic analysis revealed a reciprocal translocation involving bands 1p31 and 4q34 [t(1;4)(p31;q34)]. To the best of our knowledge, this is only the second reported case of a clonally aberrant nonossifying fibroma.

Original languageEnglish (US)
Pages (from-to)142-144
Number of pages3
JournalCancer genetics and cytogenetics
Volume142
Issue number2
DOIs
StatePublished - Apr 15 2003

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Fibroma
Cytogenetic Analysis
Tibia
Bone and Bones

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

Cite this

Nelson, M., Perry, D., Ginsburg, G., Sanger, W. G., Neff, J. R., & Bridge, J. A. (2003). Translocation (1;4)(p31;q34) in nonossifying fibroma. Cancer genetics and cytogenetics, 142(2), 142-144. https://doi.org/10.1016/S0165-4608(02)00805-1

Translocation (1;4)(p31;q34) in nonossifying fibroma. / Nelson, Marilu; Perry, Deborah; Ginsburg, Glen; Sanger, Warren G.; Neff, James R.; Bridge, Julia A.

In: Cancer genetics and cytogenetics, Vol. 142, No. 2, 15.04.2003, p. 142-144.

Research output: Contribution to journalArticle

Nelson, M, Perry, D, Ginsburg, G, Sanger, WG, Neff, JR & Bridge, JA 2003, 'Translocation (1;4)(p31;q34) in nonossifying fibroma', Cancer genetics and cytogenetics, vol. 142, no. 2, pp. 142-144. https://doi.org/10.1016/S0165-4608(02)00805-1
Nelson M, Perry D, Ginsburg G, Sanger WG, Neff JR, Bridge JA. Translocation (1;4)(p31;q34) in nonossifying fibroma. Cancer genetics and cytogenetics. 2003 Apr 15;142(2):142-144. https://doi.org/10.1016/S0165-4608(02)00805-1
Nelson, Marilu ; Perry, Deborah ; Ginsburg, Glen ; Sanger, Warren G. ; Neff, James R. ; Bridge, Julia A. / Translocation (1;4)(p31;q34) in nonossifying fibroma. In: Cancer genetics and cytogenetics. 2003 ; Vol. 142, No. 2. pp. 142-144.
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