Abstract
The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.
Original language | English (US) |
---|---|
Pages (from-to) | 723-727 |
Number of pages | 5 |
Journal | Current Opinion in Immunology |
Volume | 4 |
Issue number | 6 |
DOIs | |
State | Published - Dec 1992 |
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ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Cite this
Transgenes in autoimmunity. / Lee, Myung Shik; Sarvetnick, Nora.
In: Current Opinion in Immunology, Vol. 4, No. 6, 12.1992, p. 723-727.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Transgenes in autoimmunity
AU - Lee, Myung Shik
AU - Sarvetnick, Nora
PY - 1992/12
Y1 - 1992/12
N2 - The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.
AB - The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027092972&partnerID=8YFLogxK
U2 - 10.1016/0952-7915(92)90052-G
DO - 10.1016/0952-7915(92)90052-G
M3 - Article
C2 - 1466795
AN - SCOPUS:0027092972
VL - 4
SP - 723
EP - 727
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
SN - 0952-7915
IS - 6
ER -