Traditional management of chronic stable angina

Toby C. Trujillo, Paul P. Dobesh

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

The clinical syndrome of chronic stable angina is an age-related condition that is one common manifestation of coronary artery disease (CAD). The presence of angina significantly affects quality of life when patients must limit their activities of daily living in an effort to prevent the occurrence of anginal attacks. In addition, patients are at risk for significant complications of CAD such as myocardial infarction, heart failure, stroke, and death. Therefore, treatment should focus not only on relief of symptoms and improvements in quality of life, but also on preventing disease progression and reducing the risk of complications from CAD. All patients should be instructed on the appropriate use of sublingual nitroglycerin for the immediate treatment of anginal episodes. β-Blockers, calcium channel blockers, long-acting nitrate therapy, and ranolazine can prevent anginal symptoms. In addition, aggressive risk factor management, healthy lifestyle changes, antiplatelet agents such as aspirin, and angiotensin-converting enzyme inhibitors all should be used to prevent disease progression and occurrence of myocardial infarction or death. Many patients will be candidates for revascularization of the myocardium with either percutaneous coronary intervention or coronary artery bypass grafting for relief of symptoms as well as improvement in prognosis. Even after revascularization, patients may still require antianginal drug therapy. All patients undergoing revascularization should be guided to make appropriate lifestyle changes and to make concerted efforts to manage risk factors for CAD.

Original languageEnglish (US)
Pages (from-to)1677-1692
Number of pages16
JournalPharmacotherapy
Volume27
Issue number12 I
DOIs
StatePublished - Dec 1 2007

Fingerprint

Stable Angina
Coronary Artery Disease
Disease Progression
Myocardial Infarction
Quality of Life
Platelet Aggregation Inhibitors
Nitroglycerin
Risk Management
Calcium Channel Blockers
Percutaneous Coronary Intervention
Activities of Daily Living
Angiotensin-Converting Enzyme Inhibitors
Coronary Artery Bypass
Nitrates
Aspirin
Life Style
Myocardium
Therapeutics
Heart Failure
Stroke

Keywords

  • CAD
  • Chronic stable angina
  • Coronary artery disease
  • Treatment options

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Traditional management of chronic stable angina. / Trujillo, Toby C.; Dobesh, Paul P.

In: Pharmacotherapy, Vol. 27, No. 12 I, 01.12.2007, p. 1677-1692.

Research output: Contribution to journalReview article

Trujillo, Toby C. ; Dobesh, Paul P. / Traditional management of chronic stable angina. In: Pharmacotherapy. 2007 ; Vol. 27, No. 12 I. pp. 1677-1692.
@article{d7b44441a1224be58b547085b2fece30,
title = "Traditional management of chronic stable angina",
abstract = "The clinical syndrome of chronic stable angina is an age-related condition that is one common manifestation of coronary artery disease (CAD). The presence of angina significantly affects quality of life when patients must limit their activities of daily living in an effort to prevent the occurrence of anginal attacks. In addition, patients are at risk for significant complications of CAD such as myocardial infarction, heart failure, stroke, and death. Therefore, treatment should focus not only on relief of symptoms and improvements in quality of life, but also on preventing disease progression and reducing the risk of complications from CAD. All patients should be instructed on the appropriate use of sublingual nitroglycerin for the immediate treatment of anginal episodes. β-Blockers, calcium channel blockers, long-acting nitrate therapy, and ranolazine can prevent anginal symptoms. In addition, aggressive risk factor management, healthy lifestyle changes, antiplatelet agents such as aspirin, and angiotensin-converting enzyme inhibitors all should be used to prevent disease progression and occurrence of myocardial infarction or death. Many patients will be candidates for revascularization of the myocardium with either percutaneous coronary intervention or coronary artery bypass grafting for relief of symptoms as well as improvement in prognosis. Even after revascularization, patients may still require antianginal drug therapy. All patients undergoing revascularization should be guided to make appropriate lifestyle changes and to make concerted efforts to manage risk factors for CAD.",
keywords = "CAD, Chronic stable angina, Coronary artery disease, Treatment options",
author = "Trujillo, {Toby C.} and Dobesh, {Paul P.}",
year = "2007",
month = "12",
day = "1",
doi = "10.1592/phco.27.12.1677",
language = "English (US)",
volume = "27",
pages = "1677--1692",
journal = "Pharmacotherapy",
issn = "0277-0008",
publisher = "Pharmacotherapy Publications Inc.",
number = "12 I",

}

TY - JOUR

T1 - Traditional management of chronic stable angina

AU - Trujillo, Toby C.

AU - Dobesh, Paul P.

PY - 2007/12/1

Y1 - 2007/12/1

N2 - The clinical syndrome of chronic stable angina is an age-related condition that is one common manifestation of coronary artery disease (CAD). The presence of angina significantly affects quality of life when patients must limit their activities of daily living in an effort to prevent the occurrence of anginal attacks. In addition, patients are at risk for significant complications of CAD such as myocardial infarction, heart failure, stroke, and death. Therefore, treatment should focus not only on relief of symptoms and improvements in quality of life, but also on preventing disease progression and reducing the risk of complications from CAD. All patients should be instructed on the appropriate use of sublingual nitroglycerin for the immediate treatment of anginal episodes. β-Blockers, calcium channel blockers, long-acting nitrate therapy, and ranolazine can prevent anginal symptoms. In addition, aggressive risk factor management, healthy lifestyle changes, antiplatelet agents such as aspirin, and angiotensin-converting enzyme inhibitors all should be used to prevent disease progression and occurrence of myocardial infarction or death. Many patients will be candidates for revascularization of the myocardium with either percutaneous coronary intervention or coronary artery bypass grafting for relief of symptoms as well as improvement in prognosis. Even after revascularization, patients may still require antianginal drug therapy. All patients undergoing revascularization should be guided to make appropriate lifestyle changes and to make concerted efforts to manage risk factors for CAD.

AB - The clinical syndrome of chronic stable angina is an age-related condition that is one common manifestation of coronary artery disease (CAD). The presence of angina significantly affects quality of life when patients must limit their activities of daily living in an effort to prevent the occurrence of anginal attacks. In addition, patients are at risk for significant complications of CAD such as myocardial infarction, heart failure, stroke, and death. Therefore, treatment should focus not only on relief of symptoms and improvements in quality of life, but also on preventing disease progression and reducing the risk of complications from CAD. All patients should be instructed on the appropriate use of sublingual nitroglycerin for the immediate treatment of anginal episodes. β-Blockers, calcium channel blockers, long-acting nitrate therapy, and ranolazine can prevent anginal symptoms. In addition, aggressive risk factor management, healthy lifestyle changes, antiplatelet agents such as aspirin, and angiotensin-converting enzyme inhibitors all should be used to prevent disease progression and occurrence of myocardial infarction or death. Many patients will be candidates for revascularization of the myocardium with either percutaneous coronary intervention or coronary artery bypass grafting for relief of symptoms as well as improvement in prognosis. Even after revascularization, patients may still require antianginal drug therapy. All patients undergoing revascularization should be guided to make appropriate lifestyle changes and to make concerted efforts to manage risk factors for CAD.

KW - CAD

KW - Chronic stable angina

KW - Coronary artery disease

KW - Treatment options

UR - http://www.scopus.com/inward/record.url?scp=36949017201&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36949017201&partnerID=8YFLogxK

U2 - 10.1592/phco.27.12.1677

DO - 10.1592/phco.27.12.1677

M3 - Review article

C2 - 18041888

AN - SCOPUS:36949017201

VL - 27

SP - 1677

EP - 1692

JO - Pharmacotherapy

JF - Pharmacotherapy

SN - 0277-0008

IS - 12 I

ER -