Therapeutic studies in NZB/NZW mice.

Alfred D. Steinberg, Randall Krakauer, James L. Reinertsen, Lynell W. Klassen, David Ilfeld, J. Patton Reeves, Gary W. Williams, Tatiana Antonovych

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Spleen cells from normal mice were cultured with Concanavalin A to produce an immunosuppressive supernate. This supernate was used to treat the lupus‐like autoimmune disease of NZB/NZW mice. Such treated mice lived significantly longer than did controls, but only if treatment was initiated early in the course of the illness.

Original languageEnglish (US)
Pages (from-to)204-209
Number of pages6
JournalArthritis & Rheumatism
Volume21
Issue number2
DOIs
StatePublished - Mar 1978

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Inbred NZB Mouse
Immunosuppressive Agents
Concanavalin A
Autoimmune Diseases
Spleen
Therapeutics

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

Cite this

Steinberg, A. D., Krakauer, R., Reinertsen, J. L., Klassen, L. W., Ilfeld, D., Reeves, J. P., ... Antonovych, T. (1978). Therapeutic studies in NZB/NZW mice. Arthritis & Rheumatism, 21(2), 204-209. https://doi.org/10.1002/art.1780210205

Therapeutic studies in NZB/NZW mice. / Steinberg, Alfred D.; Krakauer, Randall; Reinertsen, James L.; Klassen, Lynell W.; Ilfeld, David; Reeves, J. Patton; Williams, Gary W.; Antonovych, Tatiana.

In: Arthritis & Rheumatism, Vol. 21, No. 2, 03.1978, p. 204-209.

Research output: Contribution to journalArticle

Steinberg, AD, Krakauer, R, Reinertsen, JL, Klassen, LW, Ilfeld, D, Reeves, JP, Williams, GW & Antonovych, T 1978, 'Therapeutic studies in NZB/NZW mice.', Arthritis & Rheumatism, vol. 21, no. 2, pp. 204-209. https://doi.org/10.1002/art.1780210205
Steinberg AD, Krakauer R, Reinertsen JL, Klassen LW, Ilfeld D, Reeves JP et al. Therapeutic studies in NZB/NZW mice. Arthritis & Rheumatism. 1978 Mar;21(2):204-209. https://doi.org/10.1002/art.1780210205
Steinberg, Alfred D. ; Krakauer, Randall ; Reinertsen, James L. ; Klassen, Lynell W. ; Ilfeld, David ; Reeves, J. Patton ; Williams, Gary W. ; Antonovych, Tatiana. / Therapeutic studies in NZB/NZW mice. In: Arthritis & Rheumatism. 1978 ; Vol. 21, No. 2. pp. 204-209.
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