The value of HIV protective epitope research for informed vaccine design against diverse viral pathogens

Victor G. Kramer, Siddappa N. Byrareddy

Research output: Contribution to journalReview article

Abstract

The success of vaccine regimens against viral pathogens hinges on the elicitation of protective responses. Hypervariable pathogens such as HIV avoid neutralization by masking protective epitopes with more immunogenic decoys. The identification of protective, conserved epitopes is crucial for future vaccine candidate design. The strategies employed for identification of HIV protective epitopes will also aid towards rational vaccine design for other viral pathogens.

Original languageEnglish (US)
Pages (from-to)935-937
Number of pages3
JournalExpert Review of Vaccines
Volume13
Issue number8
DOIs
StatePublished - Aug 2014

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Keywords

  • Epitope
  • Glycan
  • H1N1
  • HIV
  • Vaccine

ASJC Scopus subject areas

  • Immunology
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery

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