The use of granulocyte-macrophage colony-stimulating factor in bone marrow transplantation

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Abstract

GM-CSF represents an important advance in bone marrow transplantation. The drug can be given safely and does not appear to increase the risk of graft- versus-host disease or tumor relapse. This is a rare example of a new technology reducing the cost of health care. By shortening the duration of hospitalization, GM-CSF can significantly reduce the cost of a bone marrow transplant (Table 2). However, there are few data to support the conclusion that the reduction in the duration of neutropenia is associated with a superior survival. This attests to the excellent supportive care that has been developed for patients undergoing bone marrow transplantation. At present, GM-CSF has become a standard therapy in autologous bone marrow transplantation. However, the future will undoubtedly see the development of combinations of hematopoietic growth factors and/or new growth factors that will further improve our ability to perform bone marrow transplantation.

Original languageEnglish (US)
Pages (from-to)14-18
Number of pages5
JournalSeminars in hematology
Volume29
Issue number4 SUPPL. 3
StatePublished - Jan 1 1992

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ASJC Scopus subject areas

  • Hematology

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