The sixteenth iron in the nitrogenase MoFe protein

Limei Zhang, Jens T. Kaiser, Gabriele Meloni, Kun Yun Yang, Thomas Spatzal, Susana L.A. Andrade, Oliver Einsle, James B. Howard, Douglas C. Rees

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Another iron in the fire: X-ray anomalous diffraction studies on the nitrogenase MoFe protein show the presence of a mononuclear iron site, designated as Fe16, which was previously identified as either Ca2+ or Mg2+. The position of the absorption edge indicates that this site is in the oxidation state +2. The high sequence conservation of the residues coordinated to Fe16 emphasizes the potential importance of the site in nitrogenase.

Original languageEnglish (US)
Pages (from-to)10529-10532
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number40
DOIs
StatePublished - Sep 27 2013

Fingerprint

Molybdoferredoxin
Nitrogenase
Conservation
Iron
Proteins
X ray diffraction
Oxidation

Keywords

  • iron
  • metalloproteins
  • multiple-wavelength anomalous diffraction
  • nitrogen fixation
  • nitrogenases

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Zhang, L., Kaiser, J. T., Meloni, G., Yang, K. Y., Spatzal, T., Andrade, S. L. A., ... Rees, D. C. (2013). The sixteenth iron in the nitrogenase MoFe protein. Angewandte Chemie - International Edition, 52(40), 10529-10532. https://doi.org/10.1002/anie.201303877

The sixteenth iron in the nitrogenase MoFe protein. / Zhang, Limei; Kaiser, Jens T.; Meloni, Gabriele; Yang, Kun Yun; Spatzal, Thomas; Andrade, Susana L.A.; Einsle, Oliver; Howard, James B.; Rees, Douglas C.

In: Angewandte Chemie - International Edition, Vol. 52, No. 40, 27.09.2013, p. 10529-10532.

Research output: Contribution to journalArticle

Zhang, L, Kaiser, JT, Meloni, G, Yang, KY, Spatzal, T, Andrade, SLA, Einsle, O, Howard, JB & Rees, DC 2013, 'The sixteenth iron in the nitrogenase MoFe protein', Angewandte Chemie - International Edition, vol. 52, no. 40, pp. 10529-10532. https://doi.org/10.1002/anie.201303877
Zhang L, Kaiser JT, Meloni G, Yang KY, Spatzal T, Andrade SLA et al. The sixteenth iron in the nitrogenase MoFe protein. Angewandte Chemie - International Edition. 2013 Sep 27;52(40):10529-10532. https://doi.org/10.1002/anie.201303877
Zhang, Limei ; Kaiser, Jens T. ; Meloni, Gabriele ; Yang, Kun Yun ; Spatzal, Thomas ; Andrade, Susana L.A. ; Einsle, Oliver ; Howard, James B. ; Rees, Douglas C. / The sixteenth iron in the nitrogenase MoFe protein. In: Angewandte Chemie - International Edition. 2013 ; Vol. 52, No. 40. pp. 10529-10532.
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