The relationship between semantic organization and memory in obsessive-compulsive disorder

Thilo Deckersbach, Michael W. Otto, Cary R Savage, Lee Baer, Michael A. Jenike

Research output: Contribution to journalArticle

127 Citations (Scopus)

Abstract

Background: A variety of evidence suggests that frontostriatal dysfunction is involved in obsessive-compulsive disorder (OCD). This evidence includes both neuroimaging findings and results from studies using neuropsychological assessments. Previous studies have documented nonverbal memory deficits in individuals with OCD, whereas verbal learning and memory were less affected. Methods: The present study examined both verbal and nonverbal memory in a sample of 17 untreated outpatients with OCD. We also evaluated the effects of encoding strategies which are believed to be mediated by frontostriatal system functioning. Results: OCD patients were significantly impaired in both verbal and nonverbal memory performance. This deficit was correlated with impairments in organizational and semantic clustering strategies at the time of encoding. Conclusions: Deficits in organizational strategies are consistent with frontostriatal dysfunction models in OCD. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)101-107
Number of pages7
JournalPsychotherapy and Psychosomatics
Volume69
Issue number2
DOIs
StatePublished - Jan 1 2000

Fingerprint

Obsessive-Compulsive Disorder
Semantics
Verbal Learning
Memory Disorders
Neuroimaging
Cluster Analysis
Outpatients

Keywords

  • Executive functions
  • Neuropsychology
  • Nonverbal memory
  • Obsessive-compulsive disorder
  • Verbal memory

ASJC Scopus subject areas

  • Clinical Psychology
  • Applied Psychology
  • Psychiatry and Mental health

Cite this

The relationship between semantic organization and memory in obsessive-compulsive disorder. / Deckersbach, Thilo; Otto, Michael W.; Savage, Cary R; Baer, Lee; Jenike, Michael A.

In: Psychotherapy and Psychosomatics, Vol. 69, No. 2, 01.01.2000, p. 101-107.

Research output: Contribution to journalArticle

Deckersbach, Thilo ; Otto, Michael W. ; Savage, Cary R ; Baer, Lee ; Jenike, Michael A. / The relationship between semantic organization and memory in obsessive-compulsive disorder. In: Psychotherapy and Psychosomatics. 2000 ; Vol. 69, No. 2. pp. 101-107.
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