The rat misl/pvi-/locus is syntenic with myc on chromosome 7

S. Ingvarsson, Z. Wirschubsky, J. Szpirer, G. Levan, G. Klein, J. Siimegi

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Abstract

Mouse Pvt-1 and rat MIS1 are frequent proviral integration sites in retrovirally induced lymphomas. The Pvt-1 locus is also involved in mouse plasmacytoma (6; 15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-l/M\SI locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protooncogene and the MIS1/Pvt-1 locus.

Original languageEnglish (US)
Pages (from-to)174-176
Number of pages3
JournalCytogenetic and Genome Research
Volume45
Issue number3-4
DOIs
Publication statusPublished - Jan 1 1987

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ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

Cite this

Ingvarsson, S., Wirschubsky, Z., Szpirer, J., Levan, G., Klein, G., & Siimegi, J. (1987). The rat misl/pvi-/locus is syntenic with myc on chromosome 7. Cytogenetic and Genome Research, 45(3-4), 174-176. https://doi.org/10.1159/000132450