Abstract

Neurodegenerative and infectious disorders related to host genetics, aging, and environment are rapidly increasing. Drugs, vaccines, or regenerative proteins offer "real" possibilities for positively affecting disease outcomes but are limited by access across the blood-brain barrier. New developments in nanomedicine and cell based drug delivery are becoming available. These discoveries can lead to improved neurological disease outcomes. Such obstacles include the toxicities inherent in the delivery systems de novo such as immuno- and neurological dysfunctions and perturbations of blood-brain barrier function. This debate by leading experts in the field highlights the promise and perils of CNS drug delivery. Click on Supplemental HTML to watch the streaming video.

Original languageEnglish (US)
Number of pages1
JournalJournal of Neuroimmune Pharmacology
Volume3
Issue number2
DOIs
StatePublished - Jun 1 2008

Fingerprint

Blood-Brain Barrier
Webcasts
Pharmaceutical Preparations
Nanomedicine
Neurodegenerative Diseases
Vaccines
Proteins

ASJC Scopus subject areas

  • Pharmacology
  • Immunology and Allergy
  • Immunology
  • Neuroscience (miscellaneous)

Cite this

The promise and perils of CNS drug delivery : A video debate. / Gendelman, Howard Eliot; Kabanov, Alexander; Linder, James.

In: Journal of Neuroimmune Pharmacology, Vol. 3, No. 2, 01.06.2008.

Research output: Contribution to journalArticle

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