The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858

A. E. Lockyer, P. D. Olson, P. Østergaard, D. Rollinson, D. A. Johnston, S. W. Attwood, V. R. Southgate, P. Horak, S. D. Snyder, T. H. Le, T. Agatsuma, D. P. McManus, A. C. Carmichael, S. Naem, D. T J Littlewood

Research output: Contribution to journalArticle

183 Citations (Scopus)

Abstract

Schistosomes are digenean flukes, parasitic of birds, mammals and crocodiles. The family Schistosomatidae contains species of considerable medical and veterinary importance, which cause the disease schistosomiasis. Previous studies, both morphological and molecular, which have provided a good deal of information on the phylogenetics of this group, have been limited in the number of species investigated or the type or extent of molecular data used. This paper presents the most comprehensive phylogeny to date, based on the sequences of 3 genes, complete ribosomal small subunit rRNA and large ribosomal subunit rRNA, and mitochondrial cytochrome oxidase 1, sequenced from 30 taxa including at least 1 representative from 10 of the 13 known genera of the Schistosomatidae and 17 of the 20 recognized Schistosoma species. The phylogeny is examined using morphological characters, intermediate and definitive host associations and biogeography. Theories as to the origins and spread of Schistosoma are also explored. The principal findings are that Ornithobilharzia and Austrobilharzia form a sister group to the Schistosoma; mammalian schistosomes appear paraphyletic and 2 Trichobilharzia species, T. ocellata and T. szidati, seem to be synonymous. The position of Orientobilharzia within the Schistosoma is confirmed, as is an Asian origin for the Schistosoma, followed by subsequent dispersal through India and Africa.

Original languageEnglish (US)
Pages (from-to)203-224
Number of pages22
JournalParasitology
Volume126
Issue number3
DOIs
StatePublished - Mar 1 2003

Fingerprint

Schistosomatidae
Schistosoma
Phylogeny
phylogeny
Genes
genes
Large Ribosome Subunits
Small Ribosome Subunits
Alligators and Crocodiles
Trichobilharzia szidati
Trematoda
Schistosomiasis
Trichobilharzia
Electron Transport Complex IV
ribosomal RNA
Birds
schistosomiasis
crocodiles
India
Mammals

Keywords

  • Biogeography
  • Character analysis
  • Digenea
  • Host-parasite associations
  • Interrelationships

ASJC Scopus subject areas

  • Parasitology
  • Animal Science and Zoology
  • Infectious Diseases

Cite this

Lockyer, A. E., Olson, P. D., Østergaard, P., Rollinson, D., Johnston, D. A., Attwood, S. W., ... Littlewood, D. T. J. (2003). The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858. Parasitology, 126(3), 203-224. https://doi.org/10.1017/S0031182002002792

The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858. / Lockyer, A. E.; Olson, P. D.; Østergaard, P.; Rollinson, D.; Johnston, D. A.; Attwood, S. W.; Southgate, V. R.; Horak, P.; Snyder, S. D.; Le, T. H.; Agatsuma, T.; McManus, D. P.; Carmichael, A. C.; Naem, S.; Littlewood, D. T J.

In: Parasitology, Vol. 126, No. 3, 01.03.2003, p. 203-224.

Research output: Contribution to journalArticle

Lockyer, AE, Olson, PD, Østergaard, P, Rollinson, D, Johnston, DA, Attwood, SW, Southgate, VR, Horak, P, Snyder, SD, Le, TH, Agatsuma, T, McManus, DP, Carmichael, AC, Naem, S & Littlewood, DTJ 2003, 'The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858', Parasitology, vol. 126, no. 3, pp. 203-224. https://doi.org/10.1017/S0031182002002792
Lockyer, A. E. ; Olson, P. D. ; Østergaard, P. ; Rollinson, D. ; Johnston, D. A. ; Attwood, S. W. ; Southgate, V. R. ; Horak, P. ; Snyder, S. D. ; Le, T. H. ; Agatsuma, T. ; McManus, D. P. ; Carmichael, A. C. ; Naem, S. ; Littlewood, D. T J. / The phylogeny of the Schistosomatidae based on three genes with emphasis on the interrelationships of Schistosoma Weinland, 1858. In: Parasitology. 2003 ; Vol. 126, No. 3. pp. 203-224.
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AU - Rollinson, D.

AU - Johnston, D. A.

AU - Attwood, S. W.

AU - Southgate, V. R.

AU - Horak, P.

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