There was more persistent methylation of liver DNA from rats given [14C] DMN if it was given during liver regeneration, either after partial hepatectomy or a dose of CCl4 compared to otherwise untreated rats. During liver regeneration, DMN metabolism was slowed making the active metabolites available for longer.
|Original language||English (US)|
|Number of pages||4|
|Journal||Zeitschrift für Krebsforschung und Klinische Onkologie|
|Publication status||Published - Jan 1 1977|
ASJC Scopus subject areas
- Cancer Research