The inheritance of psoriasis

W. Kimberling, R. L. Dobson

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Although a number of modes of genetic transmission have been proposed in psoriasis, an autosomal dominant pattern seems most consistent with available data. This suggests that an abnormality in a structural protein may be the underlying defect in the disease. The recent finding of a possible defect in the adenyl cyclase cyclic AMP cascade in the psoriatic epidermis suggests that a receptor site on the basal cell surface is a likely place to search for an altered protein.

Original languageEnglish (US)
Pages (from-to)538-540
Number of pages3
JournalJournal of Investigative Dermatology
Volume60
Issue number6
DOIs
StatePublished - Jan 1 1973

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Psoriasis
Defects
Adenylyl Cyclases
Epidermis
Cyclic AMP
Proteins
Cells

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

The inheritance of psoriasis. / Kimberling, W.; Dobson, R. L.

In: Journal of Investigative Dermatology, Vol. 60, No. 6, 01.01.1973, p. 538-540.

Research output: Contribution to journalArticle

Kimberling, W. ; Dobson, R. L. / The inheritance of psoriasis. In: Journal of Investigative Dermatology. 1973 ; Vol. 60, No. 6. pp. 538-540.
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