The influence of heterogeneous meninges on the brain mechanics under primary blast loading

Linxia Gu, Mehdi S. Chafi, Shailesh Ganpule, Namas Chandra

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

In the modeling of brain mechanics subjected to primary blast waves, there is currently no consensus on how many biological components to be used in the brain-meninges-skull complex, and what type of constitutive models to be adopted. The objective of this study is to determine the role of layered meninges in damping the dynamic response of the brain under primary blast loadings. A composite structures composed of eight solid relevant layers (including the pia, cerebrospinal fluid (CSF), dura maters) with different mechanical properties are constructed to mimic the heterogeneous human head. A hyper-viscoelastic material model is developed to better represent the mechanical response of the brain tissue over a large strain/high frequency range applicable for blast scenarios. The effect of meninges on the brain response is examined. Results show that heterogeneous composite structures of the head have a major influence on the intracranial pressure, maximum shear stress, and maximum principal strain in the brain, which is associated with traumatic brain injuries. The meninges serving as protective layers are revealed by mitigating the dynamic response of the brain. In addition, appreciable changes of the pressure and maximum shear stress are observed on the material interfaces between layers of tissues. This may be attributed to the alternation of shock wave speed caused by the impedance mismatch.

Original languageEnglish (US)
Pages (from-to)3160-3166
Number of pages7
JournalComposites Part B: Engineering
Volume43
Issue number8
DOIs
StatePublished - Dec 1 2012

Fingerprint

Brain
Mechanics
Composite structures
Dynamic response
Shear stress
Tissue
Cerebrospinal fluid
Acoustic impedance
Constitutive models
Shock waves
Damping
Mechanical properties

Keywords

  • A. Layered structures
  • B. Interface/interphase
  • B. Mechanical properties
  • Blast wave
  • C. Finite element analysis

ASJC Scopus subject areas

  • Ceramics and Composites
  • Mechanics of Materials
  • Mechanical Engineering
  • Industrial and Manufacturing Engineering

Cite this

The influence of heterogeneous meninges on the brain mechanics under primary blast loading. / Gu, Linxia; Chafi, Mehdi S.; Ganpule, Shailesh; Chandra, Namas.

In: Composites Part B: Engineering, Vol. 43, No. 8, 01.12.2012, p. 3160-3166.

Research output: Contribution to journalArticle

Gu, Linxia ; Chafi, Mehdi S. ; Ganpule, Shailesh ; Chandra, Namas. / The influence of heterogeneous meninges on the brain mechanics under primary blast loading. In: Composites Part B: Engineering. 2012 ; Vol. 43, No. 8. pp. 3160-3166.
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