The effects of tocainide on audiological and electrophysiological responses in humans

D. W. Worthington, P. E. Brookhouser, S. M. Mohiuddin, Michael P Gorga

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study reports on the systematic audiological evaluation of 18 cardiac patients receiving tocainide, an orally administered cardiac antiarrhythmic agent. The results of an audiological site of lesion test battery were compared with auditory brain stem response (ABR) measures. Of 35 ears tested, 17 (48%) presented ABR findings consistent with retrocochlear pathology. Audiological signs of retrocochlear pathology occurred less frequently and often in patients in whom ABR results suggested normal hearing or cochlear hearing loss. These data demonstrate that an extraneous agent, in this case tocainide, can affect ABR transmission times and that it is important to recognize such possible effects in order to interpret ABR data appropriately.

Original languageEnglish (US)
Pages (from-to)179-183
Number of pages5
JournalEar and hearing
Volume6
Issue number4
DOIs
StatePublished - Jan 1 1985

Fingerprint

Tocainide
Brain Stem Auditory Evoked Potentials
Pathology
Sensorineural Hearing Loss
Hearing
Ear

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Speech and Hearing

Cite this

The effects of tocainide on audiological and electrophysiological responses in humans. / Worthington, D. W.; Brookhouser, P. E.; Mohiuddin, S. M.; Gorga, Michael P.

In: Ear and hearing, Vol. 6, No. 4, 01.01.1985, p. 179-183.

Research output: Contribution to journalArticle

Worthington, D. W. ; Brookhouser, P. E. ; Mohiuddin, S. M. ; Gorga, Michael P. / The effects of tocainide on audiological and electrophysiological responses in humans. In: Ear and hearing. 1985 ; Vol. 6, No. 4. pp. 179-183.
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