The Diagnostic Utility of the Febrile Agglutinin Tests

Terrance J. Zuerlein, Philip W. Smith

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The purpose of our study was to analyze the use of febrile agglutinin (FA) serologic tests in the diagnosis of Salmonella (typhi and paratyphi), Rickettsia, Brucella, and Francisella infections. Data were collected in a retrospective chart study of 202 titer requests covering a 42-month period at our teaching hospital. We found that no diagnoses were made by utilizing complete six-antigen FA panels. Three cases of infection were diagnosed serologically, all three with more discriminately selected single-antigen titers. These three cases each had a positive epidemiological history suggestive of disease prior to ordering FA tests. Our data suggest that the FA tests (especially the Salmonella group antigen) are an overutilized set of laboratory tests and are often difficult to interpret. It is much more important to make a diagnosis based on clinical findings and epidemiological criteria.

Original languageEnglish (US)
Pages (from-to)1211-1214
Number of pages4
JournalJAMA: The Journal of the American Medical Association
Volume254
Issue number9
DOIs
StatePublished - Sep 6 1985

Fingerprint

Agglutinins
Fever
Antigens
Francisella
Salmonella paratyphi A
Rickettsia
Salmonella typhi
Brucella
Serologic Tests
Infection
Teaching Hospitals
Salmonella
Retrospective Studies
History

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The Diagnostic Utility of the Febrile Agglutinin Tests. / Zuerlein, Terrance J.; Smith, Philip W.

In: JAMA: The Journal of the American Medical Association, Vol. 254, No. 9, 06.09.1985, p. 1211-1214.

Research output: Contribution to journalArticle

Zuerlein, Terrance J. ; Smith, Philip W. / The Diagnostic Utility of the Febrile Agglutinin Tests. In: JAMA: The Journal of the American Medical Association. 1985 ; Vol. 254, No. 9. pp. 1211-1214.
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