The development of strains, forces and nociceptor activity in retrodiscal tissues of the temporomandibular joint of male and female goats

B. Loughner, Jason J Miller, V. Broumand, B. Cooper

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Chronic pain in the temporomandibular (TM) joint is predominantly manifested in women. We examined biomechanical and neural factors that could contribute to this differential representation. Relationships between jaw rotation, soft tissue strains and soft tissue forces were examined in the goat TM joint. Strains were minimal until the jaw was rotated beyond the normal range of motion (7.25 deg). There were no significant differences in rotation-strain patterns in males and females. Stress developed as strains were introduced by jaw rotation. Gender differences were observed. Males manifested higher failure loads (15.94 ± 1.98 and 11.37 ± 2.02 N, for males and females respectively) and higher elastic stiffness than females (5.62 ± 1.19 N/mm and 1.64 ± 0.31 N/mm, for males and females respectively). Recordings were made from cell bodies in the trigeminal ganglion whose distal processes innervated the retrodiscal tissue of the temporomandibular joint of the goat (n = 48). Nociceptor reactivity was characterized with respect to the capacity to transduce mandibular rotation (rotation-interval functions; (n = 29). On the basis of established relationships between rotation, strain and tissue forces, rotation-interval functions were transformed into strain-interval and force-interval functions. Comparisons were made between nociceptor properties grouped by gender. No differences in properties were observed when nociceptors were characterized with respect to jaw rotation; however, gender differences were obtained when nociceptor reactivity was characterized with respect to retrodiscal strains or forces. Consistent with smaller failure loads, nociceptors of retrodiscal tissues of females manifested a smaller range (1.12 vs 4.33 N), force to average (1.51 vs 4.64 N), force to minimum (0.95 vs 2.48 N) and force to asymptotic discharge (2.07 vs 6.81 N). Consistent with lower elastic stiffness, nociceptors of female tissues manifested higher average strain (54.4% vs 41.9%) and peak strain (74.0% vs 58.1%) to asymptotic discharge relative to those sampled from male tissues. The implications of these findings for TM joint injury and chronic pain are considered.

Original languageEnglish (US)
Pages (from-to)311-326
Number of pages16
JournalExperimental Brain Research
Volume113
Issue number2
DOIs
StatePublished - Mar 6 1997

Fingerprint

Nociceptors
Temporomandibular Joint
Goats
Jaw
Chronic Pain
Trigeminal Ganglion
Arthralgia
Articular Range of Motion
Reference Values
Wounds and Injuries

Keywords

  • Biomechanics
  • Gender
  • Joint
  • Nociception
  • Temporomandibular

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The development of strains, forces and nociceptor activity in retrodiscal tissues of the temporomandibular joint of male and female goats. / Loughner, B.; Miller, Jason J; Broumand, V.; Cooper, B.

In: Experimental Brain Research, Vol. 113, No. 2, 06.03.1997, p. 311-326.

Research output: Contribution to journalArticle

@article{4481820dea844474a8ada9f371ca9a4e,
title = "The development of strains, forces and nociceptor activity in retrodiscal tissues of the temporomandibular joint of male and female goats",
abstract = "Chronic pain in the temporomandibular (TM) joint is predominantly manifested in women. We examined biomechanical and neural factors that could contribute to this differential representation. Relationships between jaw rotation, soft tissue strains and soft tissue forces were examined in the goat TM joint. Strains were minimal until the jaw was rotated beyond the normal range of motion (7.25 deg). There were no significant differences in rotation-strain patterns in males and females. Stress developed as strains were introduced by jaw rotation. Gender differences were observed. Males manifested higher failure loads (15.94 ± 1.98 and 11.37 ± 2.02 N, for males and females respectively) and higher elastic stiffness than females (5.62 ± 1.19 N/mm and 1.64 ± 0.31 N/mm, for males and females respectively). Recordings were made from cell bodies in the trigeminal ganglion whose distal processes innervated the retrodiscal tissue of the temporomandibular joint of the goat (n = 48). Nociceptor reactivity was characterized with respect to the capacity to transduce mandibular rotation (rotation-interval functions; (n = 29). On the basis of established relationships between rotation, strain and tissue forces, rotation-interval functions were transformed into strain-interval and force-interval functions. Comparisons were made between nociceptor properties grouped by gender. No differences in properties were observed when nociceptors were characterized with respect to jaw rotation; however, gender differences were obtained when nociceptor reactivity was characterized with respect to retrodiscal strains or forces. Consistent with smaller failure loads, nociceptors of retrodiscal tissues of females manifested a smaller range (1.12 vs 4.33 N), force to average (1.51 vs 4.64 N), force to minimum (0.95 vs 2.48 N) and force to asymptotic discharge (2.07 vs 6.81 N). Consistent with lower elastic stiffness, nociceptors of female tissues manifested higher average strain (54.4{\%} vs 41.9{\%}) and peak strain (74.0{\%} vs 58.1{\%}) to asymptotic discharge relative to those sampled from male tissues. The implications of these findings for TM joint injury and chronic pain are considered.",
keywords = "Biomechanics, Gender, Joint, Nociception, Temporomandibular",
author = "B. Loughner and Miller, {Jason J} and V. Broumand and B. Cooper",
year = "1997",
month = "3",
day = "6",
doi = "10.1007/BF02450329",
language = "English (US)",
volume = "113",
pages = "311--326",
journal = "Experimental Brain Research",
issn = "0014-4819",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - The development of strains, forces and nociceptor activity in retrodiscal tissues of the temporomandibular joint of male and female goats

AU - Loughner, B.

AU - Miller, Jason J

AU - Broumand, V.

AU - Cooper, B.

PY - 1997/3/6

Y1 - 1997/3/6

N2 - Chronic pain in the temporomandibular (TM) joint is predominantly manifested in women. We examined biomechanical and neural factors that could contribute to this differential representation. Relationships between jaw rotation, soft tissue strains and soft tissue forces were examined in the goat TM joint. Strains were minimal until the jaw was rotated beyond the normal range of motion (7.25 deg). There were no significant differences in rotation-strain patterns in males and females. Stress developed as strains were introduced by jaw rotation. Gender differences were observed. Males manifested higher failure loads (15.94 ± 1.98 and 11.37 ± 2.02 N, for males and females respectively) and higher elastic stiffness than females (5.62 ± 1.19 N/mm and 1.64 ± 0.31 N/mm, for males and females respectively). Recordings were made from cell bodies in the trigeminal ganglion whose distal processes innervated the retrodiscal tissue of the temporomandibular joint of the goat (n = 48). Nociceptor reactivity was characterized with respect to the capacity to transduce mandibular rotation (rotation-interval functions; (n = 29). On the basis of established relationships between rotation, strain and tissue forces, rotation-interval functions were transformed into strain-interval and force-interval functions. Comparisons were made between nociceptor properties grouped by gender. No differences in properties were observed when nociceptors were characterized with respect to jaw rotation; however, gender differences were obtained when nociceptor reactivity was characterized with respect to retrodiscal strains or forces. Consistent with smaller failure loads, nociceptors of retrodiscal tissues of females manifested a smaller range (1.12 vs 4.33 N), force to average (1.51 vs 4.64 N), force to minimum (0.95 vs 2.48 N) and force to asymptotic discharge (2.07 vs 6.81 N). Consistent with lower elastic stiffness, nociceptors of female tissues manifested higher average strain (54.4% vs 41.9%) and peak strain (74.0% vs 58.1%) to asymptotic discharge relative to those sampled from male tissues. The implications of these findings for TM joint injury and chronic pain are considered.

AB - Chronic pain in the temporomandibular (TM) joint is predominantly manifested in women. We examined biomechanical and neural factors that could contribute to this differential representation. Relationships between jaw rotation, soft tissue strains and soft tissue forces were examined in the goat TM joint. Strains were minimal until the jaw was rotated beyond the normal range of motion (7.25 deg). There were no significant differences in rotation-strain patterns in males and females. Stress developed as strains were introduced by jaw rotation. Gender differences were observed. Males manifested higher failure loads (15.94 ± 1.98 and 11.37 ± 2.02 N, for males and females respectively) and higher elastic stiffness than females (5.62 ± 1.19 N/mm and 1.64 ± 0.31 N/mm, for males and females respectively). Recordings were made from cell bodies in the trigeminal ganglion whose distal processes innervated the retrodiscal tissue of the temporomandibular joint of the goat (n = 48). Nociceptor reactivity was characterized with respect to the capacity to transduce mandibular rotation (rotation-interval functions; (n = 29). On the basis of established relationships between rotation, strain and tissue forces, rotation-interval functions were transformed into strain-interval and force-interval functions. Comparisons were made between nociceptor properties grouped by gender. No differences in properties were observed when nociceptors were characterized with respect to jaw rotation; however, gender differences were obtained when nociceptor reactivity was characterized with respect to retrodiscal strains or forces. Consistent with smaller failure loads, nociceptors of retrodiscal tissues of females manifested a smaller range (1.12 vs 4.33 N), force to average (1.51 vs 4.64 N), force to minimum (0.95 vs 2.48 N) and force to asymptotic discharge (2.07 vs 6.81 N). Consistent with lower elastic stiffness, nociceptors of female tissues manifested higher average strain (54.4% vs 41.9%) and peak strain (74.0% vs 58.1%) to asymptotic discharge relative to those sampled from male tissues. The implications of these findings for TM joint injury and chronic pain are considered.

KW - Biomechanics

KW - Gender

KW - Joint

KW - Nociception

KW - Temporomandibular

UR - http://www.scopus.com/inward/record.url?scp=0031040889&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031040889&partnerID=8YFLogxK

U2 - 10.1007/BF02450329

DO - 10.1007/BF02450329

M3 - Article

VL - 113

SP - 311

EP - 326

JO - Experimental Brain Research

JF - Experimental Brain Research

SN - 0014-4819

IS - 2

ER -