The chloroplast triggers developmental reprogramming when MutS HOMOLOG1 is suppressed in plants

Ying Zhi Xu, Roberto de la Rosa Santamaria, Kamaldeep S. Virdi, Maria P. Arrieta-Montiel, Fareha Razvi, Shaoqing Li, Guodong Ren, Bin Yu, Danny Alexander, Lining Guo, Xuehui Feng, Ismail M. Dweikat, Tom E. Clemente, Sally Mackenzie

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Multicellular eukaryotes demonstrate nongenetic, heritable phenotypic versatility in their adaptation to environmental changes. This inclusive inheritance is composed of interacting epigenetic, maternal, and environmental factors. Yet-unidentified maternal effects can have a pronounced influence on plant phenotypic adaptation to changing environmental conditions. To explore the control of phenotypy in higher plants, we examined the effect of a single plant nuclear gene on the expression and transmission of phenotypic variability in Arabidopsis (Arabidopsis thaliana). MutS HOMOLOG1 (MSH1) is a plant-specific nuclear gene product that functions in both mitochondria and plastids to maintain genome stability. RNA interference suppression of the gene elicits strikingly similar programmed changes in plant growth pattern in six different plant species, changes subsequently heritable independent of the RNA interference transgene. The altered phenotypes reflect multiple pathways that are known to participate in adaptation, including altered phytohormone effects for dwarfed growth and reduced internode elongation, enhanced branching, reduced stomatal density, altered leaf morphology, delayed flowering, and extended juvenility, with conversion to perennial growth pattern in short days. Some of these effects are partially reversed with the application of gibberellic acid. Genetic hemicomplementation experiments show that this phenotypic plasticity derives from changes in chloroplast state. Our results suggest that suppression of MSH1, which occurs under several forms of abiotic stress, triggers a plastidial response process that involves nongenetic inheritance.

Original languageEnglish (US)
Pages (from-to)710-720
Number of pages11
JournalPlant physiology
Volume159
Issue number2
DOIs
StatePublished - Jun 1 2012

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Chloroplasts
chloroplasts
RNA Interference
RNA interference
Arabidopsis
inheritance (genetics)
Growth
juvenility
Plant Genes
environmental factors
Plastids
Plant Growth Regulators
genes
Genomic Instability
phenotypic plasticity
maternal effect
Eukaryota
Transgenes
gibberellic acid
Epigenomics

ASJC Scopus subject areas

  • Physiology
  • Genetics
  • Plant Science

Cite this

Xu, Y. Z., de la Rosa Santamaria, R., Virdi, K. S., Arrieta-Montiel, M. P., Razvi, F., Li, S., ... Mackenzie, S. (2012). The chloroplast triggers developmental reprogramming when MutS HOMOLOG1 is suppressed in plants. Plant physiology, 159(2), 710-720. https://doi.org/10.1104/pp.112.196055

The chloroplast triggers developmental reprogramming when MutS HOMOLOG1 is suppressed in plants. / Xu, Ying Zhi; de la Rosa Santamaria, Roberto; Virdi, Kamaldeep S.; Arrieta-Montiel, Maria P.; Razvi, Fareha; Li, Shaoqing; Ren, Guodong; Yu, Bin; Alexander, Danny; Guo, Lining; Feng, Xuehui; Dweikat, Ismail M.; Clemente, Tom E.; Mackenzie, Sally.

In: Plant physiology, Vol. 159, No. 2, 01.06.2012, p. 710-720.

Research output: Contribution to journalArticle

Xu, YZ, de la Rosa Santamaria, R, Virdi, KS, Arrieta-Montiel, MP, Razvi, F, Li, S, Ren, G, Yu, B, Alexander, D, Guo, L, Feng, X, Dweikat, IM, Clemente, TE & Mackenzie, S 2012, 'The chloroplast triggers developmental reprogramming when MutS HOMOLOG1 is suppressed in plants', Plant physiology, vol. 159, no. 2, pp. 710-720. https://doi.org/10.1104/pp.112.196055
Xu YZ, de la Rosa Santamaria R, Virdi KS, Arrieta-Montiel MP, Razvi F, Li S et al. The chloroplast triggers developmental reprogramming when MutS HOMOLOG1 is suppressed in plants. Plant physiology. 2012 Jun 1;159(2):710-720. https://doi.org/10.1104/pp.112.196055
Xu, Ying Zhi ; de la Rosa Santamaria, Roberto ; Virdi, Kamaldeep S. ; Arrieta-Montiel, Maria P. ; Razvi, Fareha ; Li, Shaoqing ; Ren, Guodong ; Yu, Bin ; Alexander, Danny ; Guo, Lining ; Feng, Xuehui ; Dweikat, Ismail M. ; Clemente, Tom E. ; Mackenzie, Sally. / The chloroplast triggers developmental reprogramming when MutS HOMOLOG1 is suppressed in plants. In: Plant physiology. 2012 ; Vol. 159, No. 2. pp. 710-720.
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