That Which Bends Up

A Case Report and Literature Review of Chikungunya Virus

Shana M. Peper, Benjamin J. Monson, Trevor C VanSchooneveld, Christopher J Smith

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We present a case of chikungunya virus (CHIKV) in a 39-year-old female who developed an acute febrile illness marked by polyarthralgia and rash after returning from Saint Lucia. This epidemic-prone pathogen is increasingly likely to be encountered by primary care and hospital physicians in the coming months. The virus was first locally transmitted in the Caribbean in December 2013 and has since spread to 44 countries and 47 US states, affecting a suspected 1.2 million people. A mosquito-borne virus, CHIKV causes a severe and symmetric polyarthralgia that can relapse for months to years, creating debilitating illness and profound socioeconomic consequences. Current treatment is limited to supportive measures, which are dependent on nonsteroidal anti-inflammatory drugs. Research into immunomodulatory agents, antiviral therapies, and vaccines is ongoing. Prevention remains key in slowing the spread of disease. Patient education should focus on personal protective measures, such as insect repellant and remaining indoors, while public health departments should implement strategies to control vector breeding grounds. Given the possibility of relapsing and debilitating disease, general internists should consider CHIKV in the differential diagnosis of a returning traveler with acute onset of fever, polyarthralgia, and rash.

Original languageEnglish (US)
JournalJournal of General Internal Medicine
DOIs
StateAccepted/In press - Jul 21 2015

Fingerprint

Chikungunya virus
Arthralgia
Exanthema
Saint Lucia
Fever
Viruses
Active Immunotherapy
Primary Care Physicians
Patient Education
Culicidae
Breeding
Antiviral Agents
Insects
Differential Diagnosis
Anti-Inflammatory Agents
Public Health
Recurrence
Research
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

That Which Bends Up : A Case Report and Literature Review of Chikungunya Virus. / Peper, Shana M.; Monson, Benjamin J.; VanSchooneveld, Trevor C; Smith, Christopher J.

In: Journal of General Internal Medicine, 21.07.2015.

Research output: Contribution to journalArticle

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