T cell acute lymphoblastic leukaemia presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and cerebrospinal fluid studies

Vijaya R Bhatt, Muniba Naqi, Rajiv Bartaula, Srujitha Murukutla, Sulagna Misra, Muhammad Popalzai, Kavitha Paramanathan, Qun Dai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Leptomeningeal disease presenting with neurological dysfunction is not uncommon in leukaemia. However, it is often accompanied by abnormalities in cerebrospinal fluid (CSF) studies and/or neuroradiography. Here, the authors describe a case of a young patient presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and CSF studies, who was subsequently diagnosed to have T cell acute lymphoblastic leukaemia (T-ALL). This case highlights that neurological manifestations can be the initial presenting feature of T-ALL and can occur suddenly despite normal neuroradiography and initial CSF studies.

Original languageEnglish (US)
JournalBMJ case reports
DOIs
StatePublished - Jan 1 2012

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Neuroradiography
Oculomotor Nerve Diseases
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Cerebrospinal Fluid
Neurologic Manifestations
Leukemia

ASJC Scopus subject areas

  • Medicine(all)

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T cell acute lymphoblastic leukaemia presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and cerebrospinal fluid studies. / Bhatt, Vijaya R; Naqi, Muniba; Bartaula, Rajiv; Murukutla, Srujitha; Misra, Sulagna; Popalzai, Muhammad; Paramanathan, Kavitha; Dai, Qun.

In: BMJ case reports, 01.01.2012.

Research output: Contribution to journalArticle

Bhatt, Vijaya R ; Naqi, Muniba ; Bartaula, Rajiv ; Murukutla, Srujitha ; Misra, Sulagna ; Popalzai, Muhammad ; Paramanathan, Kavitha ; Dai, Qun. / T cell acute lymphoblastic leukaemia presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and cerebrospinal fluid studies. In: BMJ case reports. 2012.
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AU - Paramanathan, Kavitha

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