Synthesis of star-like poly[N-(2-hydroxypropyl)methacrylamide] using PAMAM dendrimer as the core

Dong Wang, Pavla Kapečková, Tamara Minko, Vajira Nanayakkara, Jindrich Kopeček

Research output: Contribution to journalConference article

9 Citations (Scopus)

Abstract

The synthesis of star-like polyhydroxypropyl methacrylamide (HPMA) copolymers using StarburstTM (PAMAM) dendrimers as the core is described. The star-like polymers were characterized by size exclusion chromatography, matrix assisted desorption/ionization-mass spectrometry, 1H nuclear magnetic resonance and ultraviolet spectroscopy. Doxorubicin was introduced into the star polymer to verify their potential for a new anticancer drug delivery system.

Original languageEnglish (US)
Pages (from-to)994-995
Number of pages2
JournalAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume41
Issue number1
StatePublished - Mar 1 2000
EventThe San Francisco Meeting - San Francisco, CA, USA
Duration: Mar 26 2000Mar 31 2000

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Dendrimers
Stars
hydroxypropyl methacrylate
Polymers
Size exclusion chromatography
Ultraviolet spectroscopy
Doxorubicin
Nuclear magnetic resonance spectroscopy
Ionization
Mass spectrometry
Desorption
Copolymers
PAMAM Starburst
Duxon

ASJC Scopus subject areas

  • Polymers and Plastics

Cite this

Synthesis of star-like poly[N-(2-hydroxypropyl)methacrylamide] using PAMAM dendrimer as the core. / Wang, Dong; Kapečková, Pavla; Minko, Tamara; Nanayakkara, Vajira; Kopeček, Jindrich.

In: American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, Vol. 41, No. 1, 01.03.2000, p. 994-995.

Research output: Contribution to journalConference article

Wang, Dong ; Kapečková, Pavla ; Minko, Tamara ; Nanayakkara, Vajira ; Kopeček, Jindrich. / Synthesis of star-like poly[N-(2-hydroxypropyl)methacrylamide] using PAMAM dendrimer as the core. In: American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 2000 ; Vol. 41, No. 1. pp. 994-995.
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