Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides

Joseph T. Paletta, Maren Pink, Bridget Foley, Suchada Rajca, Andrzej Rajca

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.

Original languageEnglish (US)
Pages (from-to)5322-5325
Number of pages4
JournalOrganic Letters
Volume14
Issue number20
DOIs
StatePublished - Oct 19 2012

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Ascorbic Acid
Derivatives
Kinetics
ascorbic acid
kinetics
synthesis
pyrrolidine

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides. / Paletta, Joseph T.; Pink, Maren; Foley, Bridget; Rajca, Suchada; Rajca, Andrzej.

In: Organic Letters, Vol. 14, No. 20, 19.10.2012, p. 5322-5325.

Research output: Contribution to journalArticle

Paletta, Joseph T. ; Pink, Maren ; Foley, Bridget ; Rajca, Suchada ; Rajca, Andrzej. / Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides. In: Organic Letters. 2012 ; Vol. 14, No. 20. pp. 5322-5325.
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