Synthesis and Biological Evaluation of Fragmented Derivatives of Tetrahydroisoquinolines. 3. Trimetoquinol Studies

Duane D. Miller, Peter F. Kador, R. Venkatraman, Dennis R. Feller

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Abstract

The synthesis of l-(3,4-dihydroxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethylamine along with the N-methyl, N-ethyl, and N-isopropyl derivatives is presented as fragmented derivatives of trimetoquinol (1). Comparative pharmacological effects of these compounds to 1 are presented and discussed.

Original languageEnglish (US)
Pages (from-to)763-766
Number of pages4
JournalJournal of Medicinal Chemistry
Volume19
Issue number6
DOIs
Publication statusPublished - Jun 1 1976

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ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

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