Susceptibility of turkeys to Georgia strain of Marek's disease virus of chicken origin.

Prem S Paul, J. H. Sautter, B. S. Pomeroy

Research output: Contribution to journalArticle

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Abstract

Two experiments were conducted to study the susceptibility of turkeys to Georgia strain of Marek's disease virus (MDV). One-day-old chickens and turkeys were experimentally inoculated with Marek's disease (MD) infective plasma (experiment 1) or tumor homogenate (experiment 2) and raised in isolation for 29 weeks. The MDV inoculums were pathogenic for chickens and turkeys and caused high mortality (chickens, 100% and turkeys, 70%). Macroscopic lesions of MD were observed in liver, spleen, lungs, proventriculus, and other viscereal organs. Microscopically, affected tissues were infiltrated with the pleomorphic population of neoplastic lymphocytes. Uninoculated turkeys did not show gross or microscopic lesion of MD. The MDV was reisolated from the experimentally inoculated, but not from the uninoculated, chickens and turkeys. Antibodies to MDV were detected in experimentally infected chickens. Uninoculated chickens and all turkeys lacked precipitating antibodies to MDV. The present study suggests that turkeys are highly susceptible to experimental infection with GA strain of MDV.

Original languageEnglish (US)
Pages (from-to)1653-1656
Number of pages4
JournalAmerican journal of veterinary research
Volume38
Issue number10
StatePublished - Oct 1 1977

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Marek Disease
Mardivirus
Chickens
chickens
Viruses
Marek disease
lesions (animal)
Proventriculus
proventriculus
antibodies
Antibodies
spleen
lymphocytes
lungs
Spleen
Lymphocytes
liver
neoplasms
Lung

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Susceptibility of turkeys to Georgia strain of Marek's disease virus of chicken origin. / Paul, Prem S; Sautter, J. H.; Pomeroy, B. S.

In: American journal of veterinary research, Vol. 38, No. 10, 01.10.1977, p. 1653-1656.

Research output: Contribution to journalArticle

Paul, Prem S ; Sautter, J. H. ; Pomeroy, B. S. / Susceptibility of turkeys to Georgia strain of Marek's disease virus of chicken origin. In: American journal of veterinary research. 1977 ; Vol. 38, No. 10. pp. 1653-1656.
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