Abstract
Advanced intra-abdominal desmoids tumors present with severe symptoms, complications or rapid growth, which lead to adverse outcomes. Our aim was to evaluate the treatment and outcome of patients with advanced intra-abdominal desmoids tumors, and develop guidelines for surgical management of these patients. We reviewed the clinical courses of 21 adult patients with advanced stage intra-abdominal desmoid tumors who presented to an intestinal rehabilitation and transplantation program. Patients with massive intestinal resection presented in two groups. The first group had a short small intestinal remnant after resection (<60 cm). These patients were poor rehabilitation candidates and eventually met criteria for transplant. The second had longer intestinal remnants and were more successfully rehabilitated and have not had complications that would lead to transplantation. Advanced intra-abdominal desmoid tumors have outcomes after resection that merit aggressive resection and planned intestinal rehabilitation and intestinal transplantation as indicated.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 31-38 |
| Number of pages | 8 |
| Journal | Cancers |
| Volume | 4 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 1 2012 |
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Keywords
- Familial adenomatous polyposis
- Intra-abdominal desmoid tumors
- Short bowel syndrome
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Surgical treatment of intra-abdominal desmoid tumors resulting in short bowel syndrome. / Wheeler, Matthew; Mercer, David F; Grant, Wendy; Botha, Jean; Langnas, Alan Norman; Thompson, Jon S.
In: Cancers, Vol. 4, No. 1, 01.03.2012, p. 31-38.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Surgical treatment of intra-abdominal desmoid tumors resulting in short bowel syndrome
AU - Wheeler, Matthew
AU - Mercer, David F
AU - Grant, Wendy
AU - Botha, Jean
AU - Langnas, Alan Norman
AU - Thompson, Jon S
PY - 2012/3/1
Y1 - 2012/3/1
N2 - Advanced intra-abdominal desmoids tumors present with severe symptoms, complications or rapid growth, which lead to adverse outcomes. Our aim was to evaluate the treatment and outcome of patients with advanced intra-abdominal desmoids tumors, and develop guidelines for surgical management of these patients. We reviewed the clinical courses of 21 adult patients with advanced stage intra-abdominal desmoid tumors who presented to an intestinal rehabilitation and transplantation program. Patients with massive intestinal resection presented in two groups. The first group had a short small intestinal remnant after resection (<60 cm). These patients were poor rehabilitation candidates and eventually met criteria for transplant. The second had longer intestinal remnants and were more successfully rehabilitated and have not had complications that would lead to transplantation. Advanced intra-abdominal desmoid tumors have outcomes after resection that merit aggressive resection and planned intestinal rehabilitation and intestinal transplantation as indicated.
AB - Advanced intra-abdominal desmoids tumors present with severe symptoms, complications or rapid growth, which lead to adverse outcomes. Our aim was to evaluate the treatment and outcome of patients with advanced intra-abdominal desmoids tumors, and develop guidelines for surgical management of these patients. We reviewed the clinical courses of 21 adult patients with advanced stage intra-abdominal desmoid tumors who presented to an intestinal rehabilitation and transplantation program. Patients with massive intestinal resection presented in two groups. The first group had a short small intestinal remnant after resection (<60 cm). These patients were poor rehabilitation candidates and eventually met criteria for transplant. The second had longer intestinal remnants and were more successfully rehabilitated and have not had complications that would lead to transplantation. Advanced intra-abdominal desmoid tumors have outcomes after resection that merit aggressive resection and planned intestinal rehabilitation and intestinal transplantation as indicated.
KW - Familial adenomatous polyposis
KW - Intra-abdominal desmoid tumors
KW - Short bowel syndrome
UR - http://www.scopus.com/inward/record.url?scp=84859085247&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859085247&partnerID=8YFLogxK
U2 - 10.3390/cancers4010031
DO - 10.3390/cancers4010031
M3 - Review article
C2 - 24213224
AN - SCOPUS:84859085247
VL - 4
SP - 31
EP - 38
JO - Cancers
JF - Cancers
SN - 2072-6694
IS - 1
ER -