Successful pregnancy after fertility-sparing local resection and uterine reconstruction for low-grade endometrial stromal sarcoma.

Abigail A. Delaney, Ashley L. Gubbels, Steve Remmenga, Paul Tomich, Kelly Molpus

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Fertility-sparing management of endometrial stromal sarcoma has been demonstrated, but reports of pregnancy after such management are rare in our current body of literature. A 16-year-old nulligravid adolescent girl presented with symptoms of menometrorrhagia and was found to have a 17-cm uterine mass. The patient underwent local resection of the mass with uterine reconstruction. Pathology revealed a low-grade endometrial stromal sarcoma. She was placed on high-dose daily megestrol acetate therapy and remained disease-free for 8 years before achieving pregnancy spontaneously. The patient underwent an uncomplicated pregnancy until 34 weeks of gestation, when she presented in preterm labor and underwent cesarean delivery of a liveborn male neonate, with no evidence of disease recurrence. Fertility-sparing management and close follow-up of low-grade endometrial stromal sarcoma may be a viable option for those desiring future fertility.

Original languageEnglish (US)
Pages (from-to)486-489
Number of pages4
JournalObstetrics and gynecology
Volume120
Issue number2 Pt 2
StatePublished - Aug 2012

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Endometrial Stromal Tumors
Fertility
Pregnancy
Endometrial Stromal Sarcoma
Megestrol Acetate
Premature Obstetric Labor
Newborn Infant
Pathology
Recurrence

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Successful pregnancy after fertility-sparing local resection and uterine reconstruction for low-grade endometrial stromal sarcoma. / Delaney, Abigail A.; Gubbels, Ashley L.; Remmenga, Steve; Tomich, Paul; Molpus, Kelly.

In: Obstetrics and gynecology, Vol. 120, No. 2 Pt 2, 08.2012, p. 486-489.

Research output: Contribution to journalArticle

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