Structure of human translin at 2.2 Å resolution

Ikuko Sugiura, Chiduko Sasaki, Tsukasa Hasegawa, Toshiyuki Kohno, Shigetoshi Sugio, Hideaki Moriyama, Masataka Kasai, Takao Matsuzaki

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The structure of human translin at 2.2 Å resolution is reported in space group C2221. Translin forms a tetramer in the asymmetric unit. Although the monomer structure is almost the same as the crystal structure of murine translin in space group P21212, the relative positions of the tetramers differ between the human and murine translins. This suggests that the multimerization of translin is flexible; the flexibility may be related to the binding to DNA/RNA.

Original languageEnglish (US)
Pages (from-to)674-679
Number of pages6
JournalActa Crystallographica Section D: Biological Crystallography
Volume60
Issue number4
DOIs
StatePublished - Apr 1 2004

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Monomers
Crystal structure
RNA
DNA
flexibility
deoxyribonucleic acid
monomers
crystal structure

ASJC Scopus subject areas

  • Structural Biology

Cite this

Structure of human translin at 2.2 Å resolution. / Sugiura, Ikuko; Sasaki, Chiduko; Hasegawa, Tsukasa; Kohno, Toshiyuki; Sugio, Shigetoshi; Moriyama, Hideaki; Kasai, Masataka; Matsuzaki, Takao.

In: Acta Crystallographica Section D: Biological Crystallography, Vol. 60, No. 4, 01.04.2004, p. 674-679.

Research output: Contribution to journalArticle

Sugiura, I, Sasaki, C, Hasegawa, T, Kohno, T, Sugio, S, Moriyama, H, Kasai, M & Matsuzaki, T 2004, 'Structure of human translin at 2.2 Å resolution', Acta Crystallographica Section D: Biological Crystallography, vol. 60, no. 4, pp. 674-679. https://doi.org/10.1107/S0907444904002549
Sugiura, Ikuko ; Sasaki, Chiduko ; Hasegawa, Tsukasa ; Kohno, Toshiyuki ; Sugio, Shigetoshi ; Moriyama, Hideaki ; Kasai, Masataka ; Matsuzaki, Takao. / Structure of human translin at 2.2 Å resolution. In: Acta Crystallographica Section D: Biological Crystallography. 2004 ; Vol. 60, No. 4. pp. 674-679.
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