Strategies for prevention of health care-associated infections in the NICU

Richard A. Polin, Susan Denson, Michael T. Brady, Lu Ann Papile, Jill E. Baley, Waldemar A. Carlo, James J. Cummings, Praveen Kumar, Rosemarie C. Tan, Kristi L. Watterberg, Carrie L. Byington, H. Dele Davies, Kathryn M. Edwards, Mary P. Glode, Mary Anne Jackson, Harry L. Keyserling, Yvonne A. Maldonado, Dennis L. Murray, Walter A. Orenstein, Gordon E. SchutzeRodney E. Willoughby, Theoklis E. Zaoutis

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

Health care-associated infections in the NICU result in increased morbidity and mortality, prolonged lengths of stay, and increased medical costs. Neonates are at high risk of acquiring health care- associated infections because of impaired host-defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of their skin, use of invasive procedures and devices, and frequent exposure to broadspectrum antibiotic agents. This clinical report reviews management and prevention of health care-associated infections in newborn infants.

Original languageEnglish (US)
Pages (from-to)e1085-e1093
JournalPediatrics
Volume129
Issue number4
DOIs
Publication statusPublished - Apr 2012

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Keywords

  • Antibiotics
  • Health care-associated infection
  • NICU
  • Neonatal icu
  • Neonate
  • Newborn
  • Nosocomial infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Polin, R. A., Denson, S., Brady, M. T., Papile, L. A., Baley, J. E., Carlo, W. A., ... Zaoutis, T. E. (2012). Strategies for prevention of health care-associated infections in the NICU. Pediatrics, 129(4), e1085-e1093. https://doi.org/10.1542/peds.2012-0145