Starving the Enemy? Feeding Behavior Shapes Host-Parasite Interactions

Jessica L. Hite, Alaina C. Pfenning, Clayton E. Cressler

Research output: Contribution to journalReview article

Abstract

The loss of appetite that typically accompanies infection or mere exposure to parasites is traditionally considered a negative byproduct of infection, benefitting neither the host nor the parasite. Numerous medical and veterinary practices directly or indirectly subvert this ‘illness-mediated anorexia’. However, the ecological factors that influence it, its effects on disease outcomes, and why it evolved remain poorly resolved. We explore how hosts use anorexia to defend against infection and how parasites manipulate anorexia to enhance transmission. Then, we use a coevolutionary model to illustrate how shifts in the magnitude of anorexia (e.g., via drugs) affect disease dynamics and virulence evolution. Anorexia could be exploited to improve disease management; we propose an interdisciplinary approach to minimize unintended consequences.

Original languageEnglish (US)
Pages (from-to)68-80
Number of pages13
JournalTrends in Ecology and Evolution
Volume35
Issue number1
DOIs
StatePublished - Jan 2020

Fingerprint

host-parasite interaction
host-parasite relationships
feeding behavior
anorexia
parasite
host use
interdisciplinary approach
virulence
parasites
drug
infection
byproducts
disease control
drugs

Keywords

  • anorexia
  • eco-immunology
  • foraging ecology
  • sickness behavior
  • virulence evolution

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics

Cite this

Starving the Enemy? Feeding Behavior Shapes Host-Parasite Interactions. / Hite, Jessica L.; Pfenning, Alaina C.; Cressler, Clayton E.

In: Trends in Ecology and Evolution, Vol. 35, No. 1, 01.2020, p. 68-80.

Research output: Contribution to journalReview article

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