Sphenoid wing meningioma progression after placement of a subcutaneous progesterone agonist contraceptive implant

John G. Piper, Kenneth A. Follett, Aldo Fantin

Research output: Contribution to journalArticle

17 Scopus citations


A CAUSAL RELATIONSHIP between sex steroids and meningioma proliferation has long been suspected. We report a case of the clinical progression of a sphenoid wing meningioma after the placement of Norplant, a subcutaneous contraceptive implant containing levonorgestrel, a progesterone agonist. Although not proof of causation, this observation lends further credence to the importance of progesterone receptors in the growth and possible treatment of meningiomas.

Original languageEnglish (US)
Pages (from-to)723-725
Number of pages3
Issue number4
Publication statusPublished - Apr 1994



  • Contraceptive
  • Hormone
  • Meningioma
  • Norplant
  • Progesterone

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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