Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte-nanoparticle complexation

Gilad Kaufman, Siamak Nejati, Raphael Sarfati, Rostislav Boltyanskiy, Michael Loewenberg, Eric R. Dufresne, Chinedum O. Osuji

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Composite microcapsules have been aggressively pursued as designed chemical entities for biomedical and other applications. Common preparations rely on multi-step, time consuming processes. Here, we present a single-step approach to fabricate such microcapsules with shells composed of nanoparticle-polyelectrolyte and protein-polyelectrolyte complexes, and demonstrate control of the mechanical and release properties of these constructs. Interfacial polyelectrolyte-nanoparticle and polyelectrolyte-protein complexation across a water-oil droplet interface results in the formation of capsules with shell thicknesses of a few μm. Silica shell microcapsules exhibited a significant plastic response at small deformations, whereas lysozyme incorporated shells displayed a more elastic response. We exploit the plasticity of nanoparticle incorporated shells to produce microcapsules with high aspect ratio protrusions by micropipette aspiration.

Original languageEnglish (US)
Pages (from-to)7478-7482
Number of pages5
JournalSoft Matter
Volume11
Issue number38
DOIs
StatePublished - Jul 7 2015

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plastic shells
Polyelectrolytes
Complexation
Capsules
Plastics
Nanoparticles
nanoparticles
proteins
lysozyme
capsules
high aspect ratio
plastic properties
plastics
oils
mechanical properties
silicon dioxide
Muramidase
vacuum
preparation
composite materials

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics

Cite this

Kaufman, G., Nejati, S., Sarfati, R., Boltyanskiy, R., Loewenberg, M., Dufresne, E. R., & Osuji, C. O. (2015). Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte-nanoparticle complexation. Soft Matter, 11(38), 7478-7482. https://doi.org/10.1039/c5sm00973a

Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte-nanoparticle complexation. / Kaufman, Gilad; Nejati, Siamak; Sarfati, Raphael; Boltyanskiy, Rostislav; Loewenberg, Michael; Dufresne, Eric R.; Osuji, Chinedum O.

In: Soft Matter, Vol. 11, No. 38, 07.07.2015, p. 7478-7482.

Research output: Contribution to journalArticle

Kaufman, G, Nejati, S, Sarfati, R, Boltyanskiy, R, Loewenberg, M, Dufresne, ER & Osuji, CO 2015, 'Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte-nanoparticle complexation', Soft Matter, vol. 11, no. 38, pp. 7478-7482. https://doi.org/10.1039/c5sm00973a
Kaufman, Gilad ; Nejati, Siamak ; Sarfati, Raphael ; Boltyanskiy, Rostislav ; Loewenberg, Michael ; Dufresne, Eric R. ; Osuji, Chinedum O. / Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte-nanoparticle complexation. In: Soft Matter. 2015 ; Vol. 11, No. 38. pp. 7478-7482.
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